A guide to naming eukaryotic circular RNAs,Nature Cell Biology

当前位置： X-MOL 学术 › Nat. Cell Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A guide to naming eukaryotic circular RNAs
Nature Cell Biology ( IF 17.3 ) Pub Date : 2023-01-19 , DOI: 10.1038/s41556-022-01066-9
Ling-Ling Chen ₁ , Albrecht Bindereif ₂ , Irene Bozzoni ₃ , Howard Y Chang ₄ , A Gregory Matera ₅ , Myriam Gorospe ₆ , Thomas B Hansen ₇ , Jørgen Kjems ₇ , Xu-Kai Ma ₈ , Jun Wei Pek ₉ , Nikolaus Rajewsky ₁₀ , Julia Salzman ₁₁ , Jeremy E Wilusz ₁₂ , Li Yang ₈ , Fangqing Zhao ₁₃

Affiliation

State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Institute of Biochemistry, Faculty of Biology and Chemistry, Justus Liebig University of Giessen, Giessen, Germany.
Department of Biology and Biotechnologies 'Charles Darwin' and IIT Center for Life Nano- & Sapienza University of Rome, Rome, Italy.
Center for Personal Dynamic Regulomes, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Integrative Program in Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.
Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Center for Molecular Medicine, Children's Hospital, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Temasek Life Sciences Laboratory, 1 Research Link National University of Singapore, Singapore, Singapore.
Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Hemholtz Association, Berlin, Germany.
Department of Biochemistry, Stanford University, Stanford, CA, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA.
Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.

Alternative splicing of eukaryotic messenger RNA transcripts often leads to the production of several mature RNAs — including linear RNAs and circular RNAs (circRNAs) — from a single gene locus. The names given to circRNAs are often ambiguous and lack consistency across studies. This Comment calls on the community to embrace a common nomenclature for naming circRNAs to ensure clarity and reproducibility.

中文翻译：

真核环状RNA命名指南

真核生物信使 RNA 转录本的选择性剪接通常会导致从单个基因位点产生多种成熟 RNA，包括线性 RNA 和环状 RNA (circRNA)。 circRNA 的名称常常含糊不清，并且在不同研究中缺乏一致性。此评论呼吁社区采用通用命名法来命名 circRNA，以确保清晰度和可重复性。

更新日期：2023-01-20

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11