Metabolic rewiring of activated macrophages promotes glycolysis and contributes to bacterial killing. A new study shows that reactive nitrogen species, released during macrophage activation, induce a profound inhibitory signal that facilitates metabolic reprogramming by modification of lipoate.

中文翻译：

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亚硝基化重塑新陈代谢

活化巨噬细胞的代谢重新布线促进糖酵解并有助于杀死细菌。一项新的研究表明，巨噬细胞激活过程中释放的活性氮会诱导一种深刻的抑制信号，通过硫辛酸的修饰促进代谢重编程。