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Non-invasive monitoring of autophagy
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2022-09-20 , DOI: 10.1038/s41551-022-00943-w Ben Loos 1 , Andre du Toit 1 , Jan-Hendrik S Hofmeyr 2
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2022-09-20 , DOI: 10.1038/s41551-022-00943-w Ben Loos 1 , Andre du Toit 1 , Jan-Hendrik S Hofmeyr 2
Affiliation
The flux of autophagosomes in heart tissue can be detected in live mice via the fluorescence and magnetic resonance properties of intravenously injected iron oxide nanoparticles decorated with fluorescent peptides cleavable by lysosomal cathepsins.
中文翻译:
自噬的无创监测
通过静脉内注射的氧化铁纳米粒子的荧光和磁共振特性,可以在活体小鼠中检测心脏组织中自噬体的通量,该纳米粒子装饰有可被溶酶体组织蛋白酶切割的荧光肽。
更新日期:2022-09-21
中文翻译:
自噬的无创监测
通过静脉内注射的氧化铁纳米粒子的荧光和磁共振特性,可以在活体小鼠中检测心脏组织中自噬体的通量,该纳米粒子装饰有可被溶酶体组织蛋白酶切割的荧光肽。