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The efficacy of the use of heparin in the emergency room in patients with acute ST-segment elevation myocardial infarction
Journal of Radiation Research and Applied Sciences ( IF 1.7 ) Pub Date : 2022-03-19 , DOI: 10.1016/j.jrras.2022.03.002
Guoxing Zuo , Ying Li , Sheng Hu , Kuan Wang , Hui Zhao , Dong Wang , Xiaoqian Qian , Xinping Du

To investigate the efficacy of the use of heparin in the emergency room in patients with acute ST-segment elevation myocardial infarction (STEMI). 200 STEMI patients undergoing primary percutaneous coronary intervention (PCI) were randomly divided into the research and control groups (heparin administration in emergency room and catheterization laboratory, respectively). The rate of thrombolysis in myocardial infarction (TIMI) grade 2 flow in the research participants was significantly higher than that in the controls ( < 0.05). The stent diameter in the research patients was smaller than that in the control participants ( < 0.05); while the stent length in the research patients was shorter than that in the controls ( < 0.05). The slow flow rate in the research patients was similar to that in the control participants ( > 0.05). There were no differences between the groups in the corrected TIMI frame counts or intraoperative complications ( > 0.05). The ST-segment resolution rate within 2 h post-PCI was 90.0% in the research patients and 83.8% in the controls ( > 0.05). There was no significant difference in the cardiac troponin and N terminal prohormone of brain natriuretic peptide (NT-proBNP) levels between the two groups post-PCI ( > 0.05). The left ventricular end-diastolic volume and left ventricular ejection fraction (LVEF) during hospitalization were similar between the groups ( > 0.05). Administering heparin to STEMI patients in the emergency room can increase the rate of coronary artery revascularization.

中文翻译:

急诊室使用肝素对急性ST段抬高型心肌梗死患者的疗效

探讨急诊室使用肝素治疗急性 ST 段抬高型心肌梗死 (STEMI) 患者的疗效。将200例接受直接经皮冠状动脉介入治疗(PCI)的STEMI患者随机分为研究组和对照组(分别在急诊室和导管室给予肝素)。研究参与者的心肌梗死 (TIMI) 2 级血流溶栓率显着高于对照组 ( < 0.05)。研究患者的支架直径小于对照参与者的支架直径(<0.05);而研究患者的支架长度短于对照组(<0.05)。研究患者的慢流速与对照参与者相似 (> 0.05)。各组之间校正的 TIMI 帧计数或术中并发症没有差异 (> 0.05)。研究患者 PCI 术后 2 小时内 ST 段恢复率为 90.0%,对照组为 83.8% (> 0.05)。 PCI术后两组心肌肌钙蛋白和N末端脑利钠肽激素原(NT-proBNP)水平无显着性差异(>0.05)。住院期间左心室舒张末期容积和左心室射血分数(LVEF)在各组之间相似(>0.05)。在急诊室对STEMI患者给予肝素可提高冠状动脉血运重建率。
更新日期:2022-03-19
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