Electrochemical reduction of carbon monoxide (CO) has recently emerged as a potential approach for obtaining high-value, multicarbon products such as acetate, while the activity and selectivity for prodution of acetate have remained low. Herein, we develop an atomically ordered copper–palladium intermetallic compound (CuPd) composed of a high density of Cu–Pd pairs that feature as catalytic sites to enrich surface *CO coverage, stabilize ethenone as a key acetate path intermediate and inhibit the hydrogen evolution reaction, thus substantially promoting acetate formation. The CuPd electrocatalyst enables a high Faradaic efficiency of 70 ± 5% for CO-to-acetate electroreduction and a high acetate partial current density of 425 mA cm⁻². Under membrane electrode assembly conditions, the CuPd electrocatalyst demonstrated a 500 h CO-to-acetate conversion at 500 mA cm⁻² with a stable acetate Faradaic efficiency of ~50%.

一氧化碳 (CO) 的电化学还原最近已成为获得高价值、多碳产品（如乙酸盐）的潜在方法，而生产乙酸盐的活性和选择性仍然很低。在此，我们开发了一种原子有序的铜-钯金属间化合物 (CuPd)，该化合物由高密度的 Cu-Pd 对组成，作为催化位点以丰富表面*CO 覆盖，稳定乙烯酮作为关键的醋酸途径中间体并抑制析氢反应，从而大大促进乙酸盐的形成。CuPd 电催化剂实现了 70 ± 5% 的高法拉第效率，用于 CO 转化为乙酸盐的电还原和 425 mA cm ^{-2的高乙酸盐分电流密度}. 在膜电极组装条件下，CuPd 电催化剂在 500 mA cm ^-2下表现出 500 小时 CO 到乙酸盐的转化，稳定的乙酸盐法拉第效率约为 50%。