当前位置: X-MOL 学术Nat. Chem. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Oxidize me to the space
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2022-03-24 , DOI: 10.1038/s41589-022-00986-9
Jing Yang 1
Affiliation  

Chemoproteomics reveals a cysteine oxidation event that inhibits the maturation process of a lysosomal protease, enabling its secretion into the extracellular space during infection-induced tumorigenesis. A recent study offers a new mechanistic paradigm for redox-dependent regulation of protein trafficking.

中文翻译:

把我氧化成空间

化学蛋白质组学揭示了抑制溶酶体蛋白酶成熟过程的半胱氨酸氧化事件,使其能够在感染诱导的肿瘤发生过程中分泌到细胞外空间。最近的一项研究为蛋白质运输的氧化还原依赖性调节提供了一种新的机制范式。
更新日期:2022-03-24
down
wechat
bug