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Comparison of phenolic compounds contained in Aquilaria leaves of different species
Journal of Natural Medicines ( IF 2.5 ) Pub Date : 2022-02-14 , DOI: 10.1007/s11418-022-01608-3
Honoka Ito 1 , Michiho Ito 1
Affiliation  

Leaves of Aquilaria plants contain a variety of phenolic compounds such as iriflophenone glycosides, mangiferin, and genkwanin. Previous studies showed that Aquilaria leaf extracts exhibit many pharmacological activities, including antidiabetic and laxative effects. However, a few studies have reported differences in the chemical content and compositions of Aquilaria species. Here, three Aquilaria species were identified using matK and trnL–trnF sequences and their leaves were analyzed by HPLC and LC/MS. Comparison of the chemical components and α-glucosidase inhibition activity of the three species showed that the level of iriflophenone glycosides in A. rugosa was higher than in A. sinensis and A. crassna. There was no difference in the α-glucosidase inhibition activity of leaf extracts of the three species, but the strength of the inhibition activity can possibly be explained by the total sum of active compounds in the leaf extracts.



中文翻译:

不同品种沉香叶中酚类化合物的比较

沉香属植物的叶子含有多种酚类化合物,例如 iriflophenone 苷、芒果苷和 genkwanin。先前的研究表明,沉香叶提取物具有许多药理活性,包括抗糖尿病和通便作用。然而,一些研究报告了沉香属物种的化学成分和组成的差异。在这里,使用mat K 和trn L - trn F 序列鉴定了三种沉香属物种,并通过 HPLC 和 LC/MS 分析了它们的叶子。化学成分和α的比较3种植物的β-葡萄糖苷酶抑制活性表明,芍药中伊氟苯酮苷的含量高于中华药和粗药三种植物叶提取物的α-葡萄糖苷酶抑制活性没有差异,但抑制活性的强弱可以用叶提取物中活性化合物的总和来解释。

更新日期:2022-02-14
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