Purpose To evaluate the ocular surface properties in epidemic keratoconjunctivitis (EKC) patients during healing process, and to detect the damage on conjunctival goblet cells. Methods Bilateral EKC patients confirmed with polymerase chain reaction (PCR) testing were included. Firstly (Group 1) and secondly (Group 2) affected eyes were compared. Ocular surface parameters were performed at the first visit and first month. Results The study included 34 eyes of 17 patients. The mean age was 44.54 ± 16.80 (21-70) years (FM/M 20/14). The ocular findings in Groups 1 and 2 were not significant. For Groups 1 and 2, OSDI was 53.53 ± 23.01 and 35.90 ± 22.19 (p 0.03), tear osmolarity was 309.12 ± 19.38 and 297.47 ± 8.27 mOsm/µL (p 0.029), OSSS was 1.00 ± 0.79 and 0.18 ± 0.39 (p 0.001), T-BUT was 3.59 ± 2.29 and 6.00 ± 1.83 s (p 0.002), and Schirmer's 1 test was 10.94 ± 8.42 and 16.76 ± 9.05 mm (p 0.061), respectively. In Groups 1 and 2, the IC was Grade (G) 0 in 23.5% and 17.6%, G1 in 35.3% and 41.2%, and G2 in 41.2% and 41.2%, respectively. The ocular surface properties were worse in Group 1 than Group 2, and the difference was significant except for Schirmer's 1 test and IC. Conclusions Dry eye disorder is a complication of EKC and may cause a significant decrease in quality of life.

中文翻译：

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病毒性结膜炎愈合过程中眼表疾病的多参数评估。

目的评价流行性角结膜炎（EKC）患者愈合过程中的眼表特性，检测结膜杯状细胞的损伤情况。方法 纳入经聚合酶链反应（PCR）检测证实的双侧 EKC 患者。首先（第 1 组）和其次（第 2 组）受影响的眼睛进行比较。在第一次访问和第一个月进行眼表参数。结果该研究包括17名患者的34只眼。平均年龄为 44.54 ± 16.80 (21-70) 岁 (FM/M 20/14)。第 1 组和第 2 组的眼部发现不显着。对于第 1 组和第 2 组，OSDI 分别为 53.53 ± 23.01 和 35.90 ± 22.19 (p = 0.03)，泪液渗透压分别为 309.12 ± 19.38 和 297.47 ± 8.27 mOsm/µL (p = 0.029)，OSSS 分别为 1.00 ± 0.79 和 0.18 ± 0.39 (p = 0.001) )，T-BUT 为 3.59 ± 2.29 和 6.00 ± 1.83 s (p = 0.002)，而 Schirmer' s 1 测试分别为 10.94 ± 8.42 和 16.76 ± 9.05 mm (p = 0.061)。在第 1 组和第 2 组中，IC 分别为 23.5% 和 17.6% 的 (G) 0 级，35.3% 和 41.2% 的 G1，以及 41.2% 和 41.2% 的 G2。第1组的眼表特性比第2组差，除Schirmer's 1检验和IC外差异显着。结论 干眼症是 EKC 的一种并发症，可能导致生活质量显着下降。