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Genetic ancestry and racial differences in prostate tumours
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2021-11-23 , DOI: 10.1038/s41585-021-00544-3
Jabril R Johnson 1 , Rick A Kittles 1
Affiliation  

A striking disproportionate burden of prostate cancer incidence and mortality exists between men of West African ancestry and men of European ancestry. Identifying distinct tumour genetic biomarkers and immunomodulating signals in patients with diverse genetic ancestry might reduce the disparities in prostate cancer prognosis, treatment outcomes and mortality in high-risk racial groups.

中文翻译:

前列腺肿瘤的遗传血统和种族差异

西非血统的男性和欧洲血统的男性之间存在着惊人的不成比例的前列腺癌发病率和死亡率负担。在具有不同遗传血统的患者中识别不同的肿瘤遗传生物标志物和免疫调节信号可能会减少高危种族群体在前列腺癌预后、治疗结果和死亡率方面的差异。
更新日期:2021-11-23
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