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Tailoring combinations of hydroxyapatite/cadmium selenite/graphene oxide based on their structure, morphology, and antibacterial activity
Journal of Inorganic and Organometallic Polymers and Materials ( IF 4 ) Pub Date : 2021-10-09 , DOI: 10.1007/s10904-021-02115-w
Mehrez E. El-Naggar 1 , Ola A. Abu Ali 2 , Dalia I. Saleh 2 , M. A. Abu-Saied 3 , M. K. Ahmed 4, 5 , E. Abdel-Fattah 6, 7
Affiliation  

Nanocomposites offer the desired properties with multi-functionality behavior. Hydroxyapatite (HAP), cadmium selenide (CdSe), and graphene oxide (GO) were combined in mono, di, and tri phases compositions. The morphology, structure, and chemical composition were investigated for HAP, CdSe, HAP/CdSe, HAP/GO and HAP/CdSe/GO using X-ray diffraction (XRD), transmission electron microscope, scanning electron microscope (SEM), and X-ray photoelectron spectroscopy (XPS). XRD shows that the crystallite size increased from 28 nm to 37 nm. SEM analysis shows the roughness average (Ra) starts from 27.8 increases till 28.8 nm for HAP and HAP/CdSe/GO, while the average maximum height of the roughness (Rtm) starts from 214.2 to 212.7 nm. The existence of HAP, CdSe, and GO was confirmed with XPS, EDX, and FTIR. The polarization behavior was investigated and the corrosion current density (Icorr) of the ternary nanocomposite reached 3.7 µA/cm2, while potential corrosion reached around − 0.3 V. It was found that the release of Cd2+ and Ca2+ ions increased upon the time of exposure up to around 23± 3 and 132 ± 4 ppm, respectively. The cell viability of osteoblasts human cell line toward the ternary nanocomposite reached 95.1 ± 3%. The antibacterial activity was studied and it was found that the inhibition zone reached around 20.4 ± 1.1 and 21.4 ± 0.9 mm against E. coli and S. aureus, respectively.



中文翻译:

基于羟基磷灰石/亚硒酸镉/氧化石墨烯的结构、形态和抗菌活性定制组合

纳米复合材料提供具有多功能行为的所需特性。羟基磷灰石 (HAP)、硒化镉 (CdSe) 和氧化石墨烯 (GO) 组合成单相、二相和三相组合物。使用 X 射线衍射 (XRD)、透射电子显微镜、扫描电子显微镜 (SEM) 和 X射线光电子能谱 (XPS)。XRD 显示晶粒尺寸从 28 nm 增加到 37 nm。SEM 分析表明,HAP 和 HAP/CdSe/GO 的粗糙度平均值 (Ra) 从 27.8 增加到 28.8 nm,而粗糙度的平均最大高度 (Rtm) 从 214.2 到 212.7 nm。XPS、EDX 和 FTIR 证实了 HAP、CdSe 和 GO 的存在。corr ) 的三元纳米复合材料达到 3.7 µA/cm 2,而电位腐蚀达到约 - 0.3 V。发现 Cd 2+和 Ca 2+离子的释放随暴露时间增加至约 23± 3 和分别为 132 ± 4 ppm。成骨细胞人类细胞系对三元纳米复合材料的细胞活力达到 95.1 ± 3%。研究了抗菌活性,发现对大肠杆菌金黄色葡萄球菌的抑菌圈分别达到了20.4±1.1和21.4±0.9mm左右。

更新日期:2021-10-09
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