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Tailoring combinations of hydroxyapatite/cadmium selenite/graphene oxide based on their structure, morphology, and antibacterial activity

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Abstract

Nanocomposites offer the desired properties with multi-functionality behavior. Hydroxyapatite (HAP), cadmium selenide (CdSe), and graphene oxide (GO) were combined in mono, di, and tri phases compositions. The morphology, structure, and chemical composition were investigated for HAP, CdSe, HAP/CdSe, HAP/GO and HAP/CdSe/GO using X-ray diffraction (XRD), transmission electron microscope, scanning electron microscope (SEM), and X-ray photoelectron spectroscopy (XPS). XRD shows that the crystallite size increased from 28 nm to 37 nm. SEM analysis shows the roughness average (Ra) starts from 27.8 increases till 28.8 nm for HAP and HAP/CdSe/GO, while the average maximum height of the roughness (Rtm) starts from 214.2 to 212.7 nm. The existence of HAP, CdSe, and GO was confirmed with XPS, EDX, and FTIR. The polarization behavior was investigated and the corrosion current density (Icorr) of the ternary nanocomposite reached 3.7 µA/cm2, while potential corrosion reached around − 0.3 V. It was found that the release of Cd2+ and Ca2+ ions increased upon the time of exposure up to around 23± 3 and 132 ± 4 ppm, respectively. The cell viability of osteoblasts human cell line toward the ternary nanocomposite reached 95.1 ± 3%. The antibacterial activity was studied and it was found that the inhibition zone reached around 20.4 ± 1.1 and 21.4 ± 0.9 mm against E. coli and S. aureus, respectively.

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References

  1. M.J. Nirmala, P.J. Shiny, V. Ernest, S.P. Das, A. Samundeeswari, A. Mukherjee, N. Chndrasekaran, Int. J. Pharm. Sci 5, 23 (2013)

    CAS  Google Scholar 

  2. L. Feng, Y. Chen, J. Ren, X. Qu, Biomaterials 32, 2930 (2011)

    Article  CAS  PubMed  Google Scholar 

  3. S. Zinatloo-Ajabshir, N. Ghasemian, M. Mousavi-Kamazani, M. Salavati-Niasari, Ultrason. Sonochem. 71, 105376 (2021)

    Article  CAS  PubMed  Google Scholar 

  4. Y. Li, Q. Wei, F. Ma, X. Li, F. Liu, M. Zhou, Acta Pharm. Sin. B 8, 349 (2018)

    Article  PubMed  PubMed Central  Google Scholar 

  5. I.Y. Kim, K. Koichi, C. Ohtsuki, Ceram. Int. 1, 1927 (2015)

    Google Scholar 

  6. Y. Sun, M. Zhang, B. Bhandari, C. Yang, Food Rev. Int. 1 (2020)

  7. Q. Li, Z. Guo, X. Zhao, T. Zhang, J. Chen, Y. Wei, Nanotechnology 31, 335501 (2020)

    Article  CAS  PubMed  Google Scholar 

  8. A.S. Karakoti, L.L. Hench, S. Seal, Jom 58, 77 (2006)

    Article  CAS  Google Scholar 

  9. S. Chaudhary, Y. Kaur, B. Jayee, G.R. Chaudhary, A. Umar, J. Clean. Prod. 190, 563 (2018)

    Article  CAS  Google Scholar 

  10. A. Ivask, A. ElBadawy, C. Kaweeteerawat, D. Boren, H. Fischer, Z. Ji, C.H. Chang, R. Liu, T. Tolaymat, D. Telesca, ACS Nano 8, 374 (2014)

    Article  CAS  PubMed  Google Scholar 

  11. I. Sabree, J.E. Gough, B. Derby, Ceram. Int. 41, 8425 (2015)

    Article  CAS  Google Scholar 

  12. R. Tarrahi, A. Movafeghi, A. Khataee, F. Rezanejad, G. Gohari, Molecules 24, 410 (2019)

    Article  PubMed Central  Google Scholar 

  13. R. Bogue, Assem. Autom. (2011)

  14. S. Zinatloo-Ajabshir, M. Mousavi-Kamazani, Ceram. Int. 46, 26548 (2020)

    Article  CAS  Google Scholar 

  15. A.M. Youssef, M.E. El-Naggar, F.M. Malhat, H.M. El Sharkawi, J. Clean. Prod. 206 (2019)

  16. S.M. Abdo, R.H. Mahmoud, M. Youssef, M.E. El-Naggar, Groundw. Sustain. Dev. 10 (2020)

  17. A. Aldalbahi, M. El-Naggar, T. Khattab, M. Abdelrahman, M. Rahaman, A. Alrehaili, M. El-Newehy, Polymers (Basel). 12, 2501 (2020)

    Article  CAS  PubMed Central  Google Scholar 

  18. M.I. Hossain, M.M. Soliman, M.E. El-Naggar, M.Z. Sultan, A. Kechi, N.R. Abdelsalam, M.A. Abu-Saied, M. Chowdhury, J. Mater. Res. Technol. 12, 1715 (2021)

    Article  CAS  Google Scholar 

  19. M.H. El-Newehy, M.E. El-Naggar, S. Alotaiby, H. El-Hamshary, M. Moydeen, S. Al-Deyab, J. Nanosci. Nanotechnol. 18, 805 (2018)

    Article  CAS  PubMed  Google Scholar 

  20. S. Sharaf, M.E. El-Naggar, Cellulose (2018)

  21. M.E. El-Naggar, A.M. Abdelgawad, A. Tripathi, O.J. Rojas, J. Environ. Chem. Eng. 5, 5754 (2017)

    Article  CAS  Google Scholar 

  22. J. Hussein, M. El-Bana, E. Refaat, M.E. El-Naggar, J. Funct. Foods 37, 441 (2017)

    Article  CAS  Google Scholar 

  23. M.E. El-Naggar, R.A. Soliman, O.M. Morsy, M.S. Abdel-Aziz, Biocatal. Agric. Biotechnol. 23, 101516 (2020)

    Article  Google Scholar 

  24. H. Safajou, M. Ghanbari, O. Amiri, H. Khojasteh, F. Namvar, S. Zinatloo-Ajabshir, M. Salavati-Niasari, Int. J. Hydrogen Energy 46, 20534 (2021)

    Article  CAS  Google Scholar 

  25. S. Zinatloo-Ajabshir, S.A. Heidari-Asil, M. Salavati-Niasari, Sep. Purif. Technol. 267, 118667 (2021)

    Article  CAS  Google Scholar 

  26. S. Zinatloo-Ajabshir, M. Mousavi-Kamazani, Ceram. Int. (2021)

  27. J. Huang, S.M. Best, W. Bonfield, T. Buckland, Acta Biomater. 6, 241 (2010)

    Article  CAS  PubMed  Google Scholar 

  28. S. Petit, T. Gode, C. Thomas, S. Dzwigaj, Y. Millot, D. Brouri, J.-M. Krafft, G. Rousse, C. Laberty-Robert, G. Costentin, Phys. Chem. Chem. Phys. 19, 9630 (2017)

    Article  CAS  PubMed  Google Scholar 

  29. S. Pushpakanth, B. Srinivasan, B. Sreedhar, T.P. Sastry, Mater. Chem. Phys. 107, 492 (2008)

    Article  CAS  Google Scholar 

  30. S. Mortazavi-Derazkola, M. Salavati-Niasari, H. Khojasteh, O. Amiri, S.M. Ghoreishi, J. Clean. Prod. 168, 39 (2017)

    Article  CAS  Google Scholar 

  31. A. Seyfoori, S.A.S. Ebrahimi, S. Omidian, S.M. Naghib, J. Taiwan Inst. Chem. Eng. 96, 503 (2019)

    Article  CAS  Google Scholar 

  32. Z. Ge, P. Li, B. Li, Y. Zhao, J. Sol-Gel. Sci. Technol. 97, 138 (2021)

    Article  CAS  Google Scholar 

  33. H. Wang, Z. Guo, F. Du, Mater. Chem. Phys. 98, 422 (2006)

    Article  CAS  Google Scholar 

  34. N. Angel, S.N. Vijayaraghavan, F. Yan, L. Kong, Nanomaterials 10, 1329 (2020)

    Article  CAS  PubMed Central  Google Scholar 

  35. W.J. Basirun, B. Nasiri-Tabrizi, S. Baradaran, Crit. Rev. Solid State Mater. Sci. 43, 177 (2018)

    Article  CAS  Google Scholar 

  36. O. Nazari, P. Gouran Orimi, M.J. Chaichi, M. Mohseni, Luminescence 34, 394 (2019)

    Article  CAS  PubMed  Google Scholar 

  37. S. Pramanik, S.K.E. Hill, B. Zhi, N.V. Hudson-Smith, J.J. Wu, J.N. White, E.A. McIntire, V.S.S.K. Kondeti, A.L. Lee, P.J. Bruggeman, Environ. Sci. Nano 5, 1890 (2018)

    Article  CAS  Google Scholar 

  38. K. Kaviyarasu, K. Kanimozhi, N. Matinise, C.M. Magdalane, G.T. Mola, J. Kennedy, M. Maaza, Mater. Sci. Eng. C 76, 1012 (2017)

    Article  CAS  Google Scholar 

  39. R. Dhar, S. Singh, A. Kumar, Bull. Mater. Sci. 38, 1247 (2015)

    Article  Google Scholar 

  40. M.S. Meikhail, A.M. Abdelghany, W.M. Awad, Egypt. J. Basic Appl. Sci. 5, 138 (2018)

    Article  Google Scholar 

  41. M. Li, Q. Liu, Z. Jia, X. Xu, Y. Cheng, Y. Zheng, T. Xi, S. Wei, Carbon N. Y. 67, 185 (2014)

    Article  CAS  Google Scholar 

  42. S. Stankovich, D.A. Dikin, G.H.B. Dommett, K.M. Kohlhaas, E.J. Zimney, E.A. Stach, R.D. Piner, S.T. Nguyen, R.S. Ruoff, Nature 442, 282 (2006)

    Article  CAS  PubMed  Google Scholar 

  43. R. Al-Wafi, S.F. Mansour, M.K. Ahmed, J. Thermoplast. Compos. Mater. 34, 536 (2021)

    Article  CAS  Google Scholar 

  44. H. Chen, S. Leng, Ceram. Int. 41, 2209 (2015)

    Article  CAS  Google Scholar 

  45. D. Lahiri, A.P. Benaduce, L. Kos, A. Agarwal, Nanotechnology 22, 355703 (2011)

    Article  PubMed  Google Scholar 

  46. C. Wan, M. Frydrych, B. Chen, Soft Matter 7, 6159 (2011)

    Article  CAS  Google Scholar 

  47. J.-L. Li, B. Tang, B. Yuan, L. Sun, X.-G. Wang, Biomaterials 34, 9519 (2013)

    Article  CAS  PubMed  Google Scholar 

  48. L. Kong, T. Zhang, M. Tang, Y. Pu, J. Nanosci. Nanotechnol. 12, 8258 (2012)

    Article  CAS  PubMed  Google Scholar 

  49. S. Baradaran, E. Moghaddam, W.J. Basirun, M. Mehrali, M. Sookhakian, M. Hamdi, M.R.N. Moghaddam, Y. Alias, Carbon N. Y. 69, 32 (2014)

    Article  CAS  Google Scholar 

  50. M.K. Ahmed, M.E. El-Naggar, A. Aldalbahi, M.H. El-Newehy, A.A. Menazea, J. Mol. Liq. 113794 (2020)

  51. S.F. Mansour, S.I. El-dek, M. Ismail, M.K. Ahmed, Biomed. Phys. Eng. Express 4, 45008 (2018)

    Article  Google Scholar 

  52. S. Rahavi, A. Monshi, R. Emadi, A. Doostmohammadi, H. Akbarian, Adv. Mater. Res. (Trans Tech Publ, 2013), pp. 28–34

  53. B. Gayathri, N. Muthukumarasamy, D. Velauthapillai, S.B. Santhosh, Arab. J. Chem. 11, 645 (2018)

    Article  Google Scholar 

  54. S.F. Mansour, S.I. El-Dek, M.K. Ahmed, Sci. Rep. 7, 43202 (2017)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  55. O. Kaygili, C. Tatar, F. Yakuphanoglu, S. Keser, J. Sol-Gel. Sci. Technol. 65, 105 (2013)

    Article  CAS  Google Scholar 

  56. M.K. Ahmed, R. Ramadan, S.I. El-dek, V. Uskoković, J. Alloys Compd. 801, 70 (2019)

    Article  CAS  Google Scholar 

  57. N.S. Awwad, M.K. Ahmed, M. Afifi, H.A. Ibrahium, Appl. Phys. A 127, 1 (2021)

    Article  Google Scholar 

  58. M.J. Lukić, L. Veselinović, M. Stevanović, J. Nunić, G. Dražič, S. Marković, D. Uskoković, Mater. Lett. 122, 296 (2014)

    Article  Google Scholar 

  59. S. Hiromoto, M. Inoue, T. Taguchi, M. Yamane, N. Ohtsu, Acta Biomater. 11, 520 (2015)

    Article  CAS  PubMed  Google Scholar 

  60. A. Janković, S. Eraković, M. Mitrić, I.Z. Matić, Z.D. Juranić, G.C.P. Tsui, C. Tang, V. Mišković-Stanković, K.Y. Rhee, S.J. Park, J. Alloys Compd. 624, 148 (2015)

    Article  Google Scholar 

  61. O. Kaygili, S. Keser, N. Bulut, T. Ates, Phys. B Condens. Matter 537, 63 (2018)

    Article  CAS  Google Scholar 

  62. D. Gopi, D. Rajeswari, S. Ramya, M. Sekar, R. d Pramod, J. Dwivedi, L. Kavitha, R. Ramaseshan, Appl. Surf. Sci. 286, 83 (2013)

    Article  CAS  Google Scholar 

  63. K. Lin, Y. Zhou, Y. Zhou, H. Qu, F. Chen, Y. Zhu, J. Chang, J. Mater. Chem. 21, 16558 (2011)

    Article  CAS  Google Scholar 

  64. V.K. Mishra, B.N. Bhattacharjee, O. Parkash, D. Kumar, S.B. Rai, J. Alloys Compd. 614, 283 (2014)

    Article  CAS  Google Scholar 

  65. R. Ospina, S.A. Rincón-Ortiz, J. Rodriguez-Pereira, Surf. Sci. Spectra 27, 14021 (2020)

    Article  CAS  Google Scholar 

  66. R. Al-Gaashani, A. Najjar, Y. Zakaria, S. Mansour, M.A. Atieh, Ceram. Int. 45, 14439 (2019)

    Article  CAS  Google Scholar 

  67. C.C. Negrila, M.V. Predoi, S.L. Iconaru, D. Predoi, Molecules 23, 2986 (2018)

    Article  PubMed Central  Google Scholar 

  68. M. Awaad, S.M. Naga, N. El-Mehalawy, Ceram. Int. 41, 7816 (2015)

    Article  CAS  Google Scholar 

  69. C.-C. Chen, C.-C. Ho, S.-Y. Lin, S.-J. Ding, Ceram. Int. 41, 5445 (2015)

    Article  CAS  Google Scholar 

  70. A.A. Menazea, S.A. Abdelbadie, M.K. Ahmed, Appl. Surf. Sci. 508, 145299 (2020)

    Article  CAS  Google Scholar 

  71. S.-L. Iconaru, M. Motelica-Heino, D. Predoi, J. Spectrosc. (2013)

  72. L.A. Zavala-Sanchez, G.A. Hirata, E. Novitskaya, K. Karandikar, M. Herrera, O.A. Graeve, ACS Biomater. Sci. Eng. 1, 1306 (2015)

    Article  CAS  PubMed  Google Scholar 

  73. A.R. Pratt, Phys. Chem. Miner. 25, 24 (1997)

    Article  CAS  Google Scholar 

  74. F.J. Al-Hasani, J. Mech. Eng. Res. Dev. 43, 233 (2020)

    Google Scholar 

  75. M. Lampin, J. Biomed. Mater. Res 36, 99 (1997)

    Article  CAS  PubMed  Google Scholar 

  76. M. Ansari, S.M. Naghib, F. Moztarzadeh, A. Salati, Ceramics-Silikáty 55, 123 (2011)

    CAS  Google Scholar 

  77. G.-Y. Jung, Y.-J. Park, J.-S. Han, J. Mater. Sci. Mater. Med. 21, 1649 (2010)

    Article  CAS  PubMed  Google Scholar 

  78. S. Basu, A. Ghosh, A. Barui, B. Basu, ACS Biomater. Sci. Eng. 4, 857 (2018)

    Article  CAS  PubMed  Google Scholar 

  79. T. Ishida, MOJ Toxicol 4, 345 (2018)

    Article  Google Scholar 

  80. T.L. Nguyen, A. Blanquet, M.P. Staiger, G.J. Dias, T.B.F. Woodfield, J. Biomed. Mater. Res. Part B Appl. Biomater. 100, 1310 (2012)

    Article  CAS  Google Scholar 

  81. Y. Zhang, The effect of surface roughness parameters on contact and wettability of solid surfaces (Iowa State University, 2007)

  82. M.K. Ahmed, R. Ramadan, M. Afifi, A.A. Menazea, J. Mater. Res. Technol. 9, 8854 (2020)

    Article  CAS  Google Scholar 

  83. X. Yang, W. Zhang, Z. Zhao, N. Li, Z. Mou, D. Sun, Y. Cai, W. Wang, Y. Lin, J. Inorg. Biochem. 167, 36 (2017)

    Article  CAS  PubMed  Google Scholar 

  84. J. Zhang, S. Zhu, K. Song, Z. Wang, Z. Han, K. Zhao, Z. Fan, X. Zhou, Q. Zhang, Mater. Lett. 267, 127527 (2020)

    Article  CAS  Google Scholar 

  85. Y.-Y. Xie, X.-H. Hu, Y.-W. Zhang, F. Wahid, L.-Q. Chu, S.-R. Jia, C. Zhong, Carbohydr. Polym. 229, 115456 (2020)

    Article  CAS  PubMed  Google Scholar 

  86. M.F.M. Yusoff, N.H.A. Kasim, W.H. Himratul-Aznita, S. Saidin, K. Genasan, T. Kamarul, Z. Radzi, Mater. Charact. 178, 111169 (2021)

    Article  Google Scholar 

  87. J. Luo, B. Mamat, Z. Yue, N. Zhang, X. Xu, Y. Li, Z. Su, C. Ma, F. Zang, Y. Wang, Colloid Interface Sci. Commun. 43, 100435 (2021)

    Article  CAS  Google Scholar 

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Acknowledgements

Taif University Researchers Supporting Project Number (TURSP-2020/220), Taif University, Taif, Saudi Arabia.

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Authors and Affiliations

  1. Textile Research Division, National Research Center (Affiliation ID: 60014618), Dokki, Cairo, Egypt

    Mehrez E. El-Naggar

  2. Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia

    Ola A. Abu Ali & Dalia I. Saleh

  3. Polymeric Materials Research Department, Advanced Technology and New Materials Research Institute, City of Scientific Research and Technological Applications (SRTACITY), 21934, New Borg El-Arab City, Alexandria, Egypt

    M. A. Abu-Saied

  4. Faculty of Nanotechnology for Postgraduate Studies, Cairo University, El‑Sheikh Zayed, 12588, Egypt

    M. K. Ahmed

  5. Department of Physics, Faculty of Science, Suez University, Suez, 43518, Egypt

    M. K. Ahmed

  6. Physics Department, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, P.O. 173, Al-Kharj, 11942, Saudi Arabia

    E. Abdel-Fattah

  7. Physics Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt

    E. Abdel-Fattah

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  1. Mehrez E. El-Naggar
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El-Naggar, M.E., Abu Ali, O.A., Abu-Saied, M.A. et al. Tailoring combinations of hydroxyapatite/cadmium selenite/graphene oxide based on their structure, morphology, and antibacterial activity. J Inorg Organomet Polym 32, 311–325 (2022). https://doi.org/10.1007/s10904-021-02115-w

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