The solvothermal reactions via the self-assemble approach produced two new metal–organic compounds, i.e., [Zn(4-cptpy)(HCOO)(H₂O)]_n·(DMF)_n (1) and [Cd₃(btc)₂(4-cptpyH)(DMF)(H₂O)₃]_n (2) (DMF is N,Nʹ-dimethylformamide, H₃btc is benzene-1,3,5-tricarboxylic acid, and 4-Hcptpy is 4-[2,6-bis(pyridine-4-yl)pyridine-4-yl]benzoic acid). Furthermore, the compounds’ luminescent performances have also been studied. Their application values against postoperative infectious endophthalmitis (PIE) were assessed and the related mechanism was explored at the same time. First of all, the activation levels of nuclear factor kappa-B (NF-κb) signaling pathway was measured with real time reverse transcription-polymerase chain reaction (RT-PCR) assay. In addition to this, the enzyme linked immunosorbent assay (ELISA) detection kit was further conducted and the and the content of inflammatory cytokines released after the cataract surgery was determined. The cytotoxicity of the compounds was also detected with CCK-8 assay.

通过自组装方法的溶剂热反应产生了两种新的金属有机化合物，即 [Zn(4-cptpy)(HCOO)(H ₂ O)] _n ·(DMF) _n ( 1 ) 和 [Cd ₃ (btc ) ₂ (4-cptpyH)(DMF)(H ₂ O) ₃ ] _n ( 2 ) (DMF是N，N′-二甲基甲酰胺，H ₃btc 是苯-1,3,5-三羧酸，4-Hcptpy 是 4-[2,6-双(吡啶-4-基)吡啶-4-基]苯甲酸)。此外，还研究了化合物的发光性能。评估了它们对术后感染性眼内炎（PIE）的应用价值，同时探讨了相关机制。首先，使用实时逆转录聚合酶链反应 (RT-PCR) 测定法测量核因子 kappa-B (NF-κb) 信号通路的激活水平。除此之外，还进一步进行了酶联免疫吸附试验（ELISA）检测试剂盒，测定了白内障手术后释放的炎性细胞因子的含量和含量。还用CCK-8法检测了化合物的细胞毒性。