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Phenolic Compounds from the Twigs of Gardenia jasminoides and their Antibacterial Activity
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2021-09-15 , DOI: 10.1007/s10600-021-03494-9
Na Luo 1, 2 , Xue Wang 1, 2 , Li-Jia Huang 1, 2 , Guang-Yu Yang 1, 3 , Liang Deng 1 , Qian Gao 1, 2 , Qi-Li Mi 2 , Wan-Li Zeng 2 , Hai-Ying Xiang 2 , Jing Li 2 , Xin Liu 2 , Ya-Dong Guo 2 , Qiu-Fen Hu 3
Affiliation  

Eight phenolic compounds (1–8), including two new compounds (1 and 2), were isolated from the twigs of Gardenia jasminoides. Their structures were determined by means of extensive 1D and 2D NMR spectroscopic studies. Compounds 1–4 were tested for their antimethicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results revealed that compounds 1–4 showed good inhibition with IZD of 12.2 ± 2.2, 13.8 ± 2.4, 15.2 ± 2.8, and 12.9 ± 2.5 mm, respectively.



中文翻译:

栀子枝条酚类化合物及其抗菌活性

从栀子的枝条中分离到了八种酚类化合物 ( 1–8 ),其中包括两种新化合物 ( 12 )。它们的结构是通过广泛的 1D 和 2D NMR 光谱研究确定的。测试了化合物1-4 的抗甲氧西林金黄色葡萄球菌(抗 MRSA)活性。结果表明,化合物1-4显示出良好的抑制作用,IZD 分别为 12.2 ± 2.2、13.8 ± 2.4、15.2 ± 2.8 和 12.9 ± 2.5 mm。

更新日期:2021-09-16
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