Eight phenolic compounds (1–8), including two new compounds (1 and 2), were isolated from the twigs of Gardenia jasminoides. Their structures were determined by means of extensive 1D and 2D NMR spectroscopic studies. Compounds 1–4 were tested for their antimethicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results revealed that compounds 1–4 showed good inhibition with IZD of 12.2 ± 2.2, 13.8 ± 2.4, 15.2 ± 2.8, and 12.9 ± 2.5 mm, respectively.
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Editorial Committee of the Administration Bureau of Chinese Plant Medicine, Flora of China, Vol. 71, Science Press, Beijing, 1999.
L. P Chen, M. X. Li, Z. Q. Yang, W. D. Tao, P. Wang, X. Y. Tian, X. L Li, and W. G. Wang, J. Ethnopharmacol., 257, 112829 (2020).
R. S. Phatak, Pharmacogn. J., 7, 254 (2015).
Y. Yu, X. L. Feng, H. Gao, Z. L. Xie, Y. Dai, X. J. Huang, H. Kurihara, W. C. Ye, Y. Zhong, and X. S.Yao, Fitoterapia, 83, 563 (2012).
H. Zhang, N. Feng, Y. T. Xu, T. X. Li, X. M. Gao, Y. Zhu, Y. S. Song, Y. N. Wang, and H. H. Wu, Chem. Biodiv., 14, e1600437 (2017a).
K. F. Peng, L. G. Yang, S. Z. Zhao, L. X. Chen, F. Zhao, and F. Qiu, Bioorg. Med. Chem. Lett., 23, 1127 (2013).
S. F. Yu, X. J. Huang, S. N. Fu, C. Wu, W. C. Ye, and G. X. Zhou, Helv. Chim. Acta, 98, 1267 (2015).
R. Uddin, M. R. Saha, N. Subhan, H. Hossain, I. A. Jahan, R. Akter, and A. Alam, Adv. Pharm. Bull., 4, 273 (2014).
L. Wang, S. Liu, X. Zhang, J. Xing, Z. Liu, and F. Song, J. Chromatogr. A, 1452, 47 (2016).
M. C. Bergonzi, C. Righeschi, B. Isacchi, and A. R. Bilia, Food Chem., 134, 1199 (2012).
R. C. Xiao, G. M. Luo, L. H. Dong, Y. Y. Zhu, J. X. Zhu, F. B. Zhang, and S. N. Wu, J. Chin. Mater. Med., 42, 4636 (2017).
D. Lu, W. Y. Zhang, Y. N. Jiang, Y. Zhang, D. B. Pan, D. Zhang, X. X. Yao, and Y. Yu, Nat. Prod. Res., 33, 2789 (2019).
Y. G. Cao, Y. L. Zhang, M. N. Zeng, M. Qi, and W. S. Feng, J. Nat. Prod., 83, 1118 (2020).
A. Alam, S. Ferdosh, K. Ghafoor, A. Hakim, A. S. Juraimi, A. Khatib, and Z. I. Sarker, Asian Pac. J. Trop. Med., 9, 402 (2016).
L. Y. Ma, S. C. Ma, F. Wei, R. C. Lin, P. P. But, S. H. Lee, and S. F. Lee, Chem. Pharm. Bull., 51, 1264 (2003).
Y. W. Sun, G. M. Liu, H. Huang, and P. Z. Yu, Phytochemistry, 75, 169 (2012).
D. Q. Yu and J. S. Yang, Handbook of Analytical Chemistry, Vol. 7, Nuclear Magnetic Resonance Spectroscopy, 2nd Ed., Chemical Industry Press, Beijing, 1999, pp. 816.
Q. F. Hu, B. Zhou, X. M. Gao, L. Y. Yang, L. D. Shu, Y. Q. Shen, G. P. Li, C. T. Che, and G. Y. Yang, J. Nat. Prod., 75, 1909 (2012).
Y. K. Li, Y. L. Meng, Y. C. Yang, Y. Qin, C. F. Xia, Y. Q. Ye, X. M. Gao, and Q. F. Hu, Phytochem. Lett., 10, 46 (2014).
Clinical and Laboratory Standards Institute, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, Approved Standard, Vol. 32, Clinical and Laboratory Standards Institute, Wayne, Pa, USA, 9th Edition, 2012.
ACKNOWLEDGMENT
This research was supported by the Foundation of China Tobacco Company (110201901021 (JY-08)), the Applied Basic Research Project of Yunnan Province (2018FB150), and Yunnan Innovative Research Team for Discovery and Comprehensive Utilization of Functional Small Molecules in Medicinal Plants.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 720–723.
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Luo, N., Wang, X., Huang, LJ. et al. Phenolic Compounds from the Twigs of Gardenia jasminoides and their Antibacterial Activity. Chem Nat Compd 57, 840–843 (2021). https://doi.org/10.1007/s10600-021-03494-9
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DOI: https://doi.org/10.1007/s10600-021-03494-9