当前位置: X-MOL 学术Chem. Commun. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Design and development of a photoswitchable DFG-out kinase inhibitor
Chemical Communications ( IF 4.3 ) Pub Date : 2021-09-07 , DOI: 10.1039/d1cc04125h
Yongjin Xu 1 , Chunxia Gao 1 , Liliana Håversen 2 , Thomas Lundbäck 3 , Joakim Andréasson 4 , Morten Grøtli 1
Affiliation  

We report the synthesis and characterisation of a photoswitchable DFG-out kinase inhibitor. Photocontrol of the target kinase in both enzymatic and living cell assays is demonstrated.

中文翻译:

光开关DFG-out激酶抑制剂的设计与开发

我们报告了光开关 DFG-out 激酶抑制剂的合成和表征。证明了在酶促和活细胞测定中对靶激酶的光控制。
更新日期:2021-09-10
down
wechat
bug