Sarcoidosis is a granulomatous disease that mainly manifests within the lungs and may thereby impair lung function. Beyond and independently from organ impairment, sarcoidosis may affect quality of life which can be quantified by questionnaires. The Leicester Cough Questionnaire (LCQ) has been developed to assess cough-related quality of life. We analysed data from a prospectively collected cohort of sarcoidosis patients for validation of the German LCQ version. Our analyses demonstrated that LCQ values add additional information beyond routinely monitored parameters (e.g. lung function). Only FeV1 and BMI slightly influence LCQ scores, where all other parameters tested did not correlate with LCQ scores. In summary, LCQ is a valuable tool providing information on the patient’ quality of life beyond routine follow-up parameters. FeV1 and BMI may represent treatable traits to reduce cough-related disease burden.

结节病是一种肉芽肿性疾病，主要表现在肺内，因此可能会损害肺功能。除了器官损伤之外，结节病还可能影响生活质量，这可以通过问卷进行量化。莱斯特咳嗽问卷 (LCQ) 旨在评估与咳嗽相关的生活质量。我们分析了来自前瞻性收集的结节病患者队列的数据，以验证德国 LCQ 版本。我们的分析表明，LCQ 值增加了常规监测参数（例如肺功能）之外的额外信息。只有 FeV1 和 BMI 对 LCQ 分数有轻微影响，而所有其他测试参数与 LCQ 分数无关。总之，LCQ 是一种有价值的工具，可提供超出常规随访参数的患者生活质量信息。