Infections due to methicillin-resistant Staphylococcus aureus (MRSA) are a growing concern for public health resulting in increase in morbidity, length of hospital stay, and cost of treatment. MRSA nasal swab screening may give clinicians additional information for decision of empiric antimicrobial agents. While increasing antibiotic resistance leads to new treatment approaches, bacteriophages are one of the most promising methods for these alternatives. It was aimed to determine the effectiveness of bacteriophages against MRSA isolates. Nasal swab samples were collected from outpatients without any evidence of infection who applied to Hatay, Mersin and Gaziantep family and immigration health centers. A series (35) were isolated from Turkish patients, and G series (64) were isolated from Syrian immigrants. Methicillin resistance was determined phenotypically and genotypically. Also, antibiotic susceptibilities of all isolates were determined against erythromycin, clindamycin, gentamicin, linezolid, rifampicin, and mupirocin. The total antimicrobial resistance rates of isolates were found to be 11%, 28%, 8%, 5%, 16%, 19%, and 29% respectively. The high susceptibility rate against ciprofloxacin (88.8%) was remarkable. The overall susceptibility of MRSA strains to ENKO, INTESTI, PYO, SES, and staphylococcal bacteriophages was 67.7%, 55.5%, 53.5%, 61.6% and 44.4%, respectively. The antibiotic susceptibility rates (except erythromycin) and efficacy of bacteriophages were higher in group A. Considering that high efficacy rates were not achieved in the study and the sensitivity rates of Turkish isolates to all phages were found to be higher than those of Syrian isolates, searching for phages in the geographic regions where the pathogen is common may be helpful to obtain suitable phages for treatment.

耐甲氧西林金黄色葡萄球菌感染耐甲氧西林金黄色葡萄球菌 (MRSA) 越来越受到公众健康的关注，导致发病率、住院时间和治疗费用的增加。MRSA 鼻拭子筛查可为临床医生提供经验性抗菌药物决策的额外信息。虽然增加的抗生素耐药性导致新的治疗方法，但噬菌体是这些替代品最有前途的方法之一。其目的是确定噬菌体对 MRSA 分离株的有效性。鼻拭子样本是从申请哈塔伊、梅尔辛和加济安泰普家庭和移民健康中心的没有任何感染证据的门诊病人中采集的。A系列（35个）是从土耳其患者身上分离出来的，G系列（64个）是从叙利亚移民身上分离出来的。甲氧西林耐药性通过表型和基因型确定。还，确定了所有分离株对红霉素、克林霉素、庆大霉素、利奈唑胺、利福平和莫匹罗星的抗生素敏感性。分离株的总抗菌素耐药率分别为 11%、28%、8%、5%、16%、19% 和 29%。对环丙沙星的高敏感性（88.8%）是显着的。MRSA菌株对ENKO、INTESTI、PYO、SES和葡萄球菌噬菌体的总体敏感性分别为67.7%、55.5%、53.5%、61.6%和44.4%。A组的抗生素敏感率（除红霉素外）和噬菌体疗效较高。考虑到该研究未达到高疗效，发现土耳其分离株对所有噬菌体的敏感率均高于叙利亚分离株，