Supramolecular chemical sensing with chemosensors has attracted considerable attention over the past two decades, and today, its technology has been used for the detection of explosives, environmentally hazardous vapors, and important biorelated molecules to the human body. Of particular, the use of polymers is indispensable for the development of chemosensors for applications since inventive polymers are capable of amplifying signals and/or binding information upon complexation of an analyte with a chemosensor. Naturally, such amplification enables us to sense a very small amount of target analytes in a complex mixture. Very recently, the author proposed a novel amplification-sensing mechanism, which is called “supramolecular allosteric signal-amplification sensing” (SASS), and has expanded to various systems that are difficult to detect by using common nonamplification or “the lock-and-key concept”-based chemosensors. In this review, the author wants to present the concept and strategy of the SASS and the related examples. The methodology proposed and the results obtained herein will further encourage the research community in the fields of polymer, supramolecular, and analytical chemistry.

在过去的二十年中，使用化学传感器进行超分子化学传感引起了相当多的关注，如今，其技术已被用于检测爆炸物、对环境有害的蒸汽和对人体重要的生物相关分子。特别地，聚合物的使用对于开发用于应用的化学传感器是必不可少的，因为本发明的聚合物能够在分析物与化学传感器复合时放大信号和/或结合信息。自然，这种放大使我们能够检测复杂混合物中极少量的目标分析物。最近，作者提出了一种新的放大传感机制，称为“超分子变构信号放大传感”（SASS），并已扩展到使用常见的非放大或基于“锁和钥匙概念”的化学传感器难以检测的各种系统。在这篇评论中，作者想介绍 SASS 的概念和策略以及相关示例。本文提出的方法论和获得的结果将进一步鼓励聚合物、超分子和分析化学领域的研究界。