Astrocytes as well as electromagnetic induction have been primarily considered as main factors in regulating neuronal firing patterns in the recent decade. In this work, an improved neuron-astrocyte model in consideration of the modulation of astrocytes and the electromagnetic induction is employed to explore the extend to which both of the factors affect the firing modes of the neurons. The “alternation mode”, defined as the alternative of neural normal spiking mode with the high-frequency bursting-like mode, clearly shows the functions of astrocytes on neurons. Moreover, the firing pattern of the neuron becomes more abnormal when astrocytes are hyper-excitable, the reason why the abnormal coupling of the astrocyte leads to the “alternation mode” of the neuron have been studied. In addition, the effect of electromagnetic induction manifests nonlinear characteristic towards neurons, complex firing modes of neurons are observed in the weaker field and a switching mode consists with quiescent and spiking mode appears when there is a higher stronger field. This approved model can reveal the normal or abnormal electric activities of neuron considered electromagnetic induction induced by the degree of excitability of the astrocyte. These results can provide potential understanding about the effects of astrocyte on neuronal activity when the coupling of electromagnetic field is considered.

近十年来，星形胶质细胞和电磁感应主要被认为是调节神经元放电模式的主要因素。在这项工作中，考虑到星形胶质细胞的调节和电磁感应，采用改进的神经元-星形胶质细胞模型来探索这两种因素对神经元放电模式的影响程度。“交替模式”，定义为神经正常脉冲模式与高频突发模式的替代，清楚地显示了星形胶质细胞对神经元的功能。此外，当星形胶质细胞过度兴奋时，神经元的放电模式变得更加异常，星形胶质细胞的异常耦合导致神经元“交替模式”的原因已被研究。此外，电磁感应效应对神经元表现出非线性特性，在较弱的场中观察到神经元的复杂放电模式，当有较高的强场时出现由静止和尖峰模式组成的切换模式。这种被批准的模型可以揭示神经元的正常或异常电活动，考虑到由星形胶质细胞的兴奋程度引起的电磁感应。当考虑电磁场的耦合时，这些结果可以提供关于星形胶质细胞对神经元活动影响的潜在理解。这种被批准的模型可以揭示神经元的正常或异常电活动，考虑到由星形胶质细胞的兴奋程度引起的电磁感应。当考虑电磁场的耦合时，这些结果可以提供关于星形胶质细胞对神经元活动影响的潜在理解。这种被批准的模型可以揭示神经元的正常或异常电活动，考虑到由星形胶质细胞的兴奋程度引起的电磁感应。当考虑电磁场的耦合时，这些结果可以提供关于星形胶质细胞对神经元活动影响的潜在理解。