The skin barrier is critical in ensuring homeostasis, yet factors influencing its development, repair, and maintenance are ill-defined. In this issue of Cell Host & Microbe, Uberoi et al. demonstrate the skin microbiota’s role in maintaining barrier integrity via AHR signaling in keratinocytes, which has implications for skin disease management.

中文翻译：

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屏障的守护者：微生物群在角质形成细胞中参与 AHR 以维持皮肤稳态

皮肤屏障对于确保体内平衡至关重要，但影响其发育、修复和维护的因素尚不明确。在本期Cell Host & Microbe中，Uberoi 等人。通过角质形成细胞中的 AHR 信号，证明皮肤微生物群在维持屏障完整性方面的作用，这对皮肤病管理具有重要意义。