Cell Host & Microbe
Volume 29, Issue 8, 11 August 2021, Pages 1213-1216
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Guardians of the barrier: Microbiota engage AHR in keratinocytes to maintain skin homeostasis

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The skin barrier is critical in ensuring homeostasis, yet factors influencing its development, repair, and maintenance are ill-defined. In this issue of Cell Host & Microbe, Uberoi et al. demonstrate the skin microbiota’s role in maintaining barrier integrity via AHR signaling in keratinocytes, which has implications for skin disease management.

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