This study presents a technique for adsorption of paclitaxel on Sylopute using ultrasonic cavitation bubbles and gas bubbles. Compared with the conventional adsorption (control), the adsorbed amount and adsorption rate constant increased, respectively, by 1.27–1.44 times and 7.44–9.71 times in ultrasonic adsorption (with mixing at 80–250 W), 1.14–1.27 times and 4.63–9.31 times in ultrasonic adsorption (without mixing at 80–250 W), and 1.06–1.19 times and 1.18–1.34 times in gas bubble-adsorption (without mixing at 1.15–9.41 L/min). As a result of investigating the adsorption mechanism in which cavitation bubbles were introduced, it was shown that microjets and shock waves produced by bubble collapse, rather than the bubble itself, drastically improve mass transport in the pores of the adsorbent, thereby completely eliminating intraparticle diffusion resistance. In the case of gas bubbles, although the intraparticle diffusion coefficient increased by 1.34–1.75 times compared with the control, there was a limitation in promoting intraparticle diffusion.

本研究提出了一种使用超声波空化气泡和气泡在 Sylopute 上吸附紫杉醇的技术。与常规吸附（对照）相比，超声吸附（80-250 W混合）的吸附量和吸附速率常数分别增加1.27-1.44倍和7.44-9.71倍，1.14-1.27倍和4.63-超声波吸附9.31倍（80-250 W不混合），气泡吸附1.06-1.19倍和1.18-1.34倍（1.15-9.41 L/min不混合）。研究引入空化气泡的吸附机制的结果表明，气泡破裂产生的微射流和冲击波，而不是气泡本身，显着改善了吸附剂孔中的传质，从而完全消除颗粒内扩散阻力。在气泡的情况下，虽然颗粒内扩散系数比对照增加了 1.34-1.75 倍，但在促进颗粒内扩散方面存在局限性。