Molecular Diversity ( IF 3.9 ) Pub Date : 2021-07-23 , DOI: 10.1007/s11030-021-10268-6 Kobra Nikoofar 1 , Narges Saheb Ekhtiari 1
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Abstract
In this research, a new multilayered magnetized bio-nanocomposite has been prepared. At first, the amino acid-based ionic liquid was obtained from L-histidine and trichloroacetic acid (L–His+CCl3CO2−), embedded on the polyethylene glycol-functionalized silicated-nanomagnetite, to prepare the final nanostructure (L–His+CCl3CO2−@PEG@SiO2-nano Fe3O4). The bio-nanocomposite was characterized by several techniques such as FT-IR, FESEM, TGA/DTG, EDAX, TEM, VSM, and XRD. The catalytic activity of the core–shell nanostructure was examined in one-pot three-component reaction between aryl aldehydes, indoles, and β-naphthol/phenols to get some new 3-(α,α-diarylmethyl)indoles under solvent-free conditions at 75 °C. Eco-friendly protocol in the absence of hazardous solvents, no observation of by-products such as bis(indolyl)methanes (BIMs), in addition to recovery and reusability of the nanostructure within 3 runs without activity loss are some highlighted notable features of the work. The reused bio-nanocomposite was also characterized through FESEM technique.
Graphic abstract
中文翻译：
将L-组氨酸三氯乙酸离子液体包埋在功能化磁铁矿（L-His+CCl3CO2-@PEG@SiO2-nano Fe3O4）上的生物纳米复合材料绿色合成3-(α,α-二芳基甲基)吲哚
摘要
在这项研究中，制备了一种新的多层磁化生物纳米复合材料。首先，从L-组氨酸和三氯乙酸 ( L -His + CCl 3 CO 2 - )中获得基于氨基酸的离子液体，包埋在聚乙二醇功能化的硅化纳米磁铁上，以制备最终的纳米结构 ( L - His + CCl 3 CO 2 - @PEG@SiO 2 -nano Fe 3 O 4）。生物纳米复合材料通过多种技术进行表征，例如 FT-IR、FESEM、TGA/DTG、EDAX、TEM、VSM 和 XRD。在无溶剂条件下，芳醛、吲哚和β-萘酚/苯酚之间的一锅三组分反应得到一些新的3-( α,α-二芳甲基)吲哚，考察了核壳纳米结构的催化活性在 75 °C。在没有危险溶剂的情况下的环保协议，没有观察到副产物，如双（吲哚基）甲烷（BIM），除了在 3 次运行中纳米结构的回收和可重复使用性而没有活性损失之外，这些是该技术的一些突出显着特征工作。重复使用的生物纳米复合材料还通过 FESEM 技术进行了表征。
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