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Green synthesis of some 3-(α,α-diarylmethyl)indoles by bio-nanocomposite from embedding L–histidinium trichloroacetate ionic liquid on functionalized magnetite (L–His+CCl3CO2−@PEG@SiO2–nano Fe3O4)

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Abstract

In this research, a new multilayered magnetized bio-nanocomposite has been prepared. At first, the amino acid-based ionic liquid was obtained from L-histidine and trichloroacetic acid (L–His+CCl3CO2−), embedded on the polyethylene glycol-functionalized silicated-nanomagnetite, to prepare the final nanostructure (L–His+CCl3CO2−@PEG@SiO2-nano Fe3O4). The bio-nanocomposite was characterized by several techniques such as FT-IR, FESEM, TGA/DTG, EDAX, TEM, VSM, and XRD. The catalytic activity of the core–shell nanostructure was examined in one-pot three-component reaction between aryl aldehydes, indoles, and β-naphthol/phenols to get some new 3-(α,α-diarylmethyl)indoles under solvent-free conditions at 75 °C. Eco-friendly protocol in the absence of hazardous solvents, no observation of by-products such as bis(indolyl)methanes (BIMs), in addition to recovery and reusability of the nanostructure within 3 runs without activity loss are some highlighted notable features of the work. The reused bio-nanocomposite was also characterized through FESEM technique.

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Acknowledgements

The authors appreciate Alzahra University for financial support of this work.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Physics and Chemistry, Alzahra University, Tehran, Iran

    Kobra Nikoofar & Narges Saheb Ekhtiari

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  1. Kobra Nikoofar
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Correspondence to Kobra Nikoofar.

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Nikoofar, K., Saheb Ekhtiari, N. Green synthesis of some 3-(α,α-diarylmethyl)indoles by bio-nanocomposite from embedding L–histidinium trichloroacetate ionic liquid on functionalized magnetite (L–His+CCl3CO2−@PEG@SiO2–nano Fe3O4). Mol Divers 26, 1425–1439 (2022). https://doi.org/10.1007/s11030-021-10268-6

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