Abstract

Stereoselective synthesis of sarmentine has been achieved via iron-catalyzed cross-coupling of pentylmagnesium bromide with ethyl (2E,4E)-5-chloropenta-2,4-dienoate obtained by one-pot oxidation–olefination of readily available (2E)-3-chloroprop-2-en-1-ol.

中文翻译：

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铁催化合成沙门汀

摘要

沙门汀的立体选择性合成是通过溴化戊基镁与 (2 E ,4 E )-5-氯五-2,4-二烯酸乙酯的铁催化交叉偶联实现的，通过一锅氧化 - 烯化现成的 (2 E )-3-chloroprop-2-en-1-ol。