Recent Opportunities and Challenges in Selective C-H Functionalization of Methyl Azaarenes: A Highlight from 2010 to 2020 Studies,Current Organic Synthesis

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Recent Opportunities and Challenges in Selective C-H Functionalization of Methyl Azaarenes: A Highlight from 2010 to 2020 Studies
Current Organic Synthesis ( IF 1.7 ) Pub Date : 2021-11-30 , DOI: 10.2174/1566524021666210614141628
Fahimeh Abedinifar ₁ , Mohammad Mahdavi ₁ , Mehdi Asadi ₁ , Haleh Hamedifar ₂ , Samira Ansari ₂ , Bagher Larijani ₁

Affiliation

Azaarenes are unique scaffolds that are frequently found in pharmaceuticals. Herein we have summarized the recent synthetic available methods in C–H functionalization of methylazaarenes from 2010 to 2020. Multiple approaches involving halogenation, alkylation via different methods, alkenylation, oxidative functionalization, and cyclization of the methylazaarenes will be discussed in this review.

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