Purpose

Schistosomiasis is one of the leading chronic parasitic diseases in Ethiopia. We aimed to summarize the prevalence of S. mansoni in human and Biomphalaria snails as well as risk factors in Ethiopia.

Methods

Literature search was carried out from Scopus, Google Scholar, Science Direct and PubMed which reported Schistosoma mansoni infection in human and Biomphalaria snails in Ethiopia. The overall prevalence was estimated by a random-effect model and heterogeneities among studies were assessed by I² test.

Results

A total of 178,251 participants and 1,097 snails were tested for the presence of S. mansoni in the eligible studies. The pooled prevalence of S. mansoni was 32.5% (95% CI 28.0–37.0) and 15.9% (95% CI − 5.6–37.5) in human and Biomphalaria snails in Ethiopia, respectively. The highest pooled prevalence was 43.2% (95% CI 27.3–59.1) in South Nations and National Peoples region while the lowest pooled prevalence was 25% (95% CI 19.3–30.7) observed in the Afar region. Interestingly, the pooled prevalence of S. mansoni declined from 40.7% (95% CI 33–48.4) to 22.4% (95% CI 18.5–26.3) after the launching of mass drug administration (MDA). The analysis of risk factors showed that swimming habit (OR, 2.78; 95% CI 2.35–3.21) and participation in irrigation (OR, 2.69; 95% CI 1.45–3.73) were independent predictors for S. mansoni infection.

Conclusion

This study revealed that about one-third of human and nearly 16% of Biomphalaria snails were infected with S. mansoni in Ethiopia. This review indicated that the prevalence of S. mansoni declined after the implementation of MDA. This study highlights the importance of further integrated approaches for better control of schistosomiasis in Ethiopia.

中文翻译：

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埃塞俄比亚曼氏血吸虫的患病率和相关风险因素在人类和生物指肠蜗牛中：系统评价和荟萃分析

目的

血吸虫病是埃塞俄比亚主要的慢性寄生虫病之一。我们旨在总结人类和Biomphalaria蜗牛中S. mansoni的流行情况以及埃塞俄比亚的危险因素。

方法

从 Scopus、Google Scholar、Science Direct 和 PubMed 进行文献检索，这些文献报道了埃塞俄比亚曼氏血吸虫感染和Biomphalaria蜗牛。通过随机效应模型估计总体患病率，通过I ²检验评估研究之间的异质性。

结果

在符合条件的研究中，共有 178,251 名参与者和 1,097 只蜗牛接受了曼氏沙门氏菌的检测。在埃塞俄比亚的人类和Biomphalaria蜗牛中S. mansoni的综合患病率分别为 32.5% (95% CI 28.0–37.0) 和 15.9% (95% CI - 5.6–37.5) 。南部国家和民族地区的最高汇总患病率为 43.2% (95% CI 27.3–59.1)，而在阿法尔地区观察到的最低合并患病率为 25% (95% CI 19.3–30.7)。有趣的是， S. mansoni的合并流行率在大规模药物管理 (MDA) 启动后，这一比例从 40.7% (95% CI 33–48.4) 下降到 22.4% (95% CI 18.5–26.3)。风险因素分析表明，游泳习惯（OR，2.78；95% CI 2.35-3.21）和参与灌溉（OR，2.69；95% CI 1.45-3.73）是曼氏沙门氏菌感染的独立预测因素。

结论

这项研究表明，埃塞俄比亚约有三分之一的人类和近 16% 的Biomphalaria蜗牛感染了曼氏沙门氏菌。该评价表明，实施 MDA 后曼氏沙门氏菌的流行率有所下降。本研究强调了进一步综合方法以更好地控制埃塞俄比亚血吸虫病的重要性。