Acute promyelocytic leukemia is a distinct subset of acute myeloid leukemia with characteristic clinical, morphological and genetic features. The gene product PML-RAR alpha resulting from reciprocal t(15;17) translocation, plays a pivotal role in the pathogenesis of acute promyelocytic leukemia and classified as favorable cytogenetic features. We are describing an unusual additional chromosomal abnormality t(2;3) in APL patient.

中文翻译：

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伴有 t(2;3) 的急性早幼粒细胞白血病：一种不寻常的额外染色体异常

急性早幼粒细胞白血病是急性髓性白血病的一个独特亚型，具有典型的临床、形态学和遗传特征。由相互 t(15;17) 易位产生的基因产物 PML-RAR α 在急性早幼粒细胞白血病的发病机制中起着关键作用，并被归类为有利的细胞遗传学特征。我们正在描述 APL 患者中不寻常的额外染色体异常 t(2;3)。