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Acute Promyelocytic Leukemia with t(2;3): An Unusual Additional Chromosomal Abnormality

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Abstract

Acute promyelocytic leukemia is a distinct subset of acute myeloid leukemia with characteristic clinical, morphological and genetic features. The gene product PML-RAR alpha resulting from reciprocal t(15;17) translocation, plays a pivotal role in the pathogenesis of acute promyelocytic leukemia and classified as favorable cytogenetic features. We are describing an unusual additional chromosomal abnormality t(2;3) in APL patient.

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References

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Authors and Affiliations

  1. Laboratory Oncology Unit, Dr BRAIRCH, All India Institute of Medical Sciences, New Delhi, 110029, India

    Smeeta Gajendra

  2. Cancer Cytogenetics Department, HBCH & MPMMMCH, Varanashi, India

    Anil Kumar Yadav

  3. Department of Hematopathology, Medanta – The Medicity Hospital, Sector 38, Gurgaon, 122001, India

    Manorama Bhargava

Authors
  1. Smeeta Gajendra
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  2. Anil Kumar Yadav
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  3. Manorama Bhargava
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Correspondence to Smeeta Gajendra.

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Gajendra, S., Yadav, A.K. & Bhargava, M. Acute Promyelocytic Leukemia with t(2;3): An Unusual Additional Chromosomal Abnormality. Indian J Hematol Blood Transfus 38, 202–203 (2022). https://doi.org/10.1007/s12288-021-01468-z

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  • DOI: https://doi.org/10.1007/s12288-021-01468-z

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