Using rat and mouse models of neurogenic, ethanol-induced, and indometacin-induced damage to the gastric mucosa we demonstrated that course preventive treatment with flavonoid complex from aerial parts of Lychnis chalcedonica L. increased the resistance of gastric mucosa to ulcerogenic factors of different etiology. The gastroprotective effect of the phytocomplex in a dose range of 16-1600 μg/kg was comparable with that of the reference drug plantaglucide and was superior to that of the reference drugs eleutherococcus extract and methyluracil in the therapeutic doses. The antiulcerogenic activity of Lychnis chalcedonica flavonoid complex considerably exceeded activity of Lychnis chalcedonica L. extract demonstrated in our previous experiments.

使用神经源性、乙醇诱导和消炎痛诱导的胃黏膜损伤的大鼠和小鼠模型，我们证明了用来自荔枝的地上部分的类黄酮复合物进行的过程预防性治疗增加了胃黏膜对不同病因的溃疡因子的抵抗力. 植物复合物在16-1600μg/kg剂量范围内的胃保护作用与参考药物植物糖苷相当，在治疗剂量上优于参考药物刺五加和甲基尿嘧啶。Lychnis chalcedonica类黄酮复合物的抗溃疡活性大大超过了我们之前的实验中证明的Lychnis chalcedonica L. 提取物的活性。