当前位置: X-MOL 学术Synlett › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Photoredox Enabled Decarboxylative Synthesis of Unnatural α-Amino Acids
Synlett ( IF 1.7 ) Pub Date : 2021-05-05 , DOI: 10.1055/a-1499-8679
Markus D. Kärkäs , Andrey Shatskiy

Recently, development of general synthetic routes to unnatural α-amino acids has gained a significant momentum, driven by the high demand for such building blocks in fundamental research within molecular and structural biology, as well as for development of new pharmaceuticals. Herein, we highlight the recent progress in employing photoredox-mediated synthetic methods for accessing unnatural α-amino acids with a focus on various decarboxylative radical-based strategies.

中文翻译:

Photoredox 使非天然 α-氨基酸的脱羧合成成为可能

最近,由于分子和结构生物学基础研究以及新药物开发对此类构建模块的高需求,非天然 α-氨基酸的通用合成路线的开发获得了显着的推动。在此,我们重点介绍了使用光氧化还原介导的合成方法获取非天然 α-氨基酸方面的最新进展,重点是各种基于脱羧基的策略。
更新日期:2021-06-23
down
wechat
bug