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Phospholipases C from the Genus Bacillus: Biological Role, Properties, and Fields of Application
Russian Journal of Bioorganic Chemistry ( IF 1.1 ) Pub Date : 2021-06-11 , DOI: 10.1134/s1068162021030134
Yu. A. Merkulyeva , D. N. Shcherbakov , E. A. Sharlaeva , V. Yu. Chirkova

Abstract—

Phospholipases are enzymes of the class of hydrolases that catalyze the cleavage of bonds in phospholipids; they are found in almost all organisms. Enzymes of microbial origin are of the greatest interest. The popularity of bacterial enzymes is due to their huge variety and technological properties: high specific activity, thermal stability, and wide substrate specificity. The production of recombinant bacterial phospholipases and their improvement remain an urgent task, for which it is necessary to deepen and systematize knowledge about the enzymes of this group. This review describes the properties, structure, and mode of action of bacterial phospholipases C, which are widely used in various areas of human practice: scientific research, medicine, food, chemical industry, etc.



中文翻译:

芽孢杆菌属的磷脂酶 C:生物学作用、特性和应用领域

摘要-

磷脂酶是催化磷脂中键断裂的水解酶类的酶;它们几乎存在于所有生物体中。微生物来源的酶是最令人感兴趣的。细菌酶的流行是由于其种类繁多和技术特性:高比活性、热稳定性和广泛的底物特异性。重组细菌磷脂酶的生产及其改进仍然是一项紧迫的任务,需要深化和系统化有关该类酶的知识。这篇综述描述了细菌磷脂酶 C 的特性、结构和作用方式,它们广泛应用于人类实践的各个领域:科学研究、医学、食品、化工等。

更新日期:2021-06-11
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