Rapid on-site evaluation of fine-needle aspiration cytology is time-consuming and requires specialized cytopathology staff. Mobile Rose^® is a newly developed device for rapid on-site evaluation of fine-needle aspiration cytology. This study aimed to investigate the potential role of Mobile Rose^® in reducing delayed repeated aspiration of the thyroid. A total of 120 cytological samples were collected and observed using Mobile Rose^® after fine-needle aspiration cytology between September and October 2020, with immediate assessment of minimal or no cell clusters after conventional smear preparation. After qualifying and scoring, needle washout materials were prepared using the BD CytoRich^TM method and correlated with cytology results. The average turn-around time of Mobile Rose^® was found to be 1.5 minutes. Sensitivity, specificity, positive predictive value, and negative predictive value were 94.4%, 100%, 100%, and 57.1%, respectively. False-negative results were attributed to small aggregates of cells that were difficult to distinguish from the background and artifacts. Mobile Rose^® may represent an important innovation for rapid on-site evaluation that is fast, has high diagnostic performance, does not require the presence of specialized cytology staff, and can reduce delayed repeated aspiration of the thyroid gland. However, further minor improvements and confirmation are required.

细针抽吸细胞学的快速现场评估非常耗时，并且需要专门的细胞病理学人员。Mobile Rose ^®是一种新开发的设备，用于对细针抽吸细胞学进行快速现场评估。本研究旨在调查 Mobile Rose ^®在减少甲状腺延迟性反复抽吸中的潜在作用。在 2020 年 9 月至 2020 年 10 月期间，在细针抽吸细胞学检查后，使用 Mobile Rose ^®收集并观察了总共 120 个细胞学样本，并在常规涂片制备后立即评估最小或没有细胞簇。合格和评分后，使用 BD CytoRich ^TM制备针头冲洗材料方法并与细胞学结果相关。Mobile Rose ^®的平均周转时间为1.5 分钟。敏感性、特异性、阳性预测值和阴性预测值分别为94.4%、100%、100%和57.1%。假阴性结果归因于难以与背景和伪影区分开来的小细胞聚集体。Mobile Rose ^®可能代表了快速现场评估的一项重要创新，它具有快速、高诊断性能、不需要专门的细胞学人员在场，并且可以减少延迟的甲状腺重复抽吸。但是，还需要进一步的小改进和确认。