Purpose of Review

Mönckeberg’s medial sclerosis (MMS) is a chronic, non-inflammatory degenerative condition affecting primarily the tunica media of muscular arteries resulting in their calcification. The purpose of this comprehensive review is to describe MMS as it appears in the literature, in the context of headache and facial pain. Understanding the etiopathology, the associated conditions, and the differential diagnoses is important in managing MMS.

Recent Findings

Management of MMS primarily depends upon identification of its associated conditions and their treatment. Due to the rare incidence and inadequate literature on MMS presenting with headaches, the diagnosis of the pain and the entity itself is challenging.

Summary

MMS is characterized by associated systemic conditions and absence of inflammatory markers. It can mimic giant cell arteritis (GCA) and other pain entities. An interdisciplinary approach involving appropriate specialties is recommended.

中文翻译：

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Monckeberg 的内侧硬化是头痛和面部疼痛的原因

审查目的

Mönckeberg 内侧硬化症 (MMS) 是一种慢性、非炎症性退行性疾病，主要影响肌肉动脉的中膜，导致其钙化。本综合综述的目的是在头痛和面部疼痛的背景下描述文献中出现的 MMS。了解病因、相关疾病和鉴别诊断对于管理 MMS 很重要。

最近的发现

MMS 的管理主要取决于对其相关病症的识别及其治疗。由于头痛的 MMS 发病率罕见且文献不足，因此疼痛和实体本身的诊断具有挑战性。

概括

MMS 的特征是相关的全身性疾病和炎症标志物的缺失。它可以模拟巨细胞动脉炎 (GCA) 和其他疼痛实体。建议采用涉及适当专业的跨学科方法。