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Hypoxia-inducible factor 2 inhibitors show promise in advanced kidney cancer
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2021-06-03 , DOI: 10.1038/s41585-021-00487-9
Natalie Burrows 1, 2 , Patrick H Maxwell 1, 2
Affiliation  

A new phase I clinical trial has demonstrated that belzutifan provides a route to sustained inhibition of hypoxia-inducible factor 2α in humans that is well tolerated and could be useful in the treatment of advanced clear cell kidney cancer.

中文翻译:

缺氧诱导因子 2 抑制剂在晚期肾癌中显示出希望

一项新的 I 期临床试验表明,belzutifan 提供了一种在人体中持续抑制缺氧诱导因子 2α 的途径,该途径具有良好的耐受性,可用于治疗晚期透明细胞肾癌。
更新日期:2021-06-03
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