The rapid progress of nanomedicine field has a great influence on the different tumor therapeutic trends. It achieves a potential targeting of the therapeutic agent to the tumor site with neglectable exposure of the normal tissue. In nuclear medicine, nanocarriers have been employed for targeted delivery of therapeutic radioisotopes to the malignant tissues. This systemic radiotherapy is employed to overcome the external radiation therapy drawbacks. This review overviews studies concerned with investigation of different nanoparticles as promising carriers for targeted radiotherapy. It discusses the employment of different nanovehicles for achievement of the synergistic effect of targeted radiotherapy with other tumor therapeutic modalities such as hyperthermia and photodynamic therapy. Radiosensitization utilizing different nanosensitizer loaded nanoparticles has also been discussed briefly as one of the nanomedicine approach in radiotherapy.

中文翻译：

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纳米技术在靶向放射性核素癌症治疗中的应用：单一疗法、联合疗法和放射增敏

纳米医学领域的快速发展对不同的肿瘤治疗趋势有很大影响。它实现了治疗剂对肿瘤部位的潜在靶向，而正常组织的暴露可忽略不计。在核医学中，纳米载体已被用于将治疗性放射性同位素靶向递送至恶性组织。这种全身放射治疗用于克服外部放射治疗的缺点。本综述概述了有关研究不同纳米粒子作为靶向放射治疗的有前途的载体的研究。它讨论了不同纳米载体的使用，以实现靶向放疗与其他肿瘤治疗方式（如热疗和光动力疗法）的协同效应。