Spinal cord injury (SCI) is a debilitating condition which often leads to a severe disability and ultimately impact patient’s physical, psychological, and social well-being. The management of acute SCI has evolved over the couple of decades due to improved understanding of injury mechanisms and increasing knowledge of disease. Currently, the early management of acute SCI patient includes pharmacological agents, surgical intervention and newly experimental neuroprotective strategies. However, many controversial areas are still surrounding in the current treatment strategies for acute SCI, including the optimal timing of surgical intervention, early versus delayed decompression outcome benefits, the use of methylprednisolone. Due to the lack of consensus, the optimal standard of care has been varied across treatment centres. The authors have shed a light on the current updates on early treatment approaches and neuroprotective strategies in the initial management of acute SCI in order to protect the early neurologic injury and reduce the future disability.

中文翻译：

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急性脊髓损伤早期治疗中各种治疗方法的最新进展

脊髓损伤 (SCI) 是一种使人衰弱的疾病，通常会导致严重的残疾，并最终影响患者的身体、心理和社会福祉。几十年来，由于对损伤机制的理解加深和疾病知识的增加，急性 SCI 的管理得到了发展。目前，急性 SCI 患者的早期管理包括药物制剂、手术干预和新的实验性神经保护策略。然而，目前急性 SCI 的治疗策略仍存在许多有争议的领域，包括手术干预的最佳时机、早期与延迟减压结果的益处、甲基强的松龙的使用。由于缺乏共识，各个治疗中心的最佳护理标准各不相同。