Psychedelic drugs are well-known for transiently altering perception, and in particular, for their visual effects. Although scientific interest into the substances’ effects on perception increased during the first era of psychedelic research during the early to mid-20th century, there is currently no source where these findings have been synthesized. In addressing this gap, the current narrative review found that psychedelics were examined for their influences across all levels of the visual system (e.g., retinal, cortical, subcortical, simple visual processing, complex imagery, hallucinations). Psychedelics were also shown to affect auditory discrimination/generalization, neural correlates of auditory processing, and led to auditory hallucinations in subsets of participants. Several studies demonstrated that psychedelics can distort representations of body schema and time perception. Concerns regarding methodological standards of this era are a limitation to the findings and are discussed. Collectively, this review preserves and increases the accessibility of the work done by pioneering psychedelic/perception researchers, synthesizes findings, and critically analyzes areas of discrepancy to inform future studies.

中文翻译：

---

迷幻药物和感知：第一个研究时代的叙述性回顾

迷幻药以瞬时改变感知，尤其是其视觉效果而闻名。尽管在 20 世纪早期到中期的第一个迷幻研究时代，人们对​​物质对感知的影响的科学兴趣增加了，但目前还没有合成这些发现的来源。在解决这一差距时，当前的叙述性审查发现，迷幻药对视觉系统各个层面（例如，视网膜、皮层、皮层下、简单的视觉处理、复杂的图像、幻觉）的影响进行了检查。迷幻药也被证明会影响听觉辨别/泛化、听觉处理的神经相关性，并导致部分参与者出现幻听。几项研究表明，迷幻药会扭曲身体图式和时间感知的表征。对这个时代的方法学标准的担忧是对调查结果的限制，并进行了讨论。总体而言，本次审查保留并增加了先驱迷幻/感知研究人员所做工作的可访问性，综合了发现，并批判性地分析了差异领域，为未来的研究提供信息。