The Katjang goat is the only indigenous domestic goat breed in Malaysia. Following a national baseline survey from 2001 to 2002, this breed was reported to the FAO as being at risk of extinction. In this study, 36 microsatellite markers were screened, and 25 polymorphic markers were used to analyze the genetic structure of the Katjang goat breed in Peninsular Malaysia. A sample set of data derived from another 10 populations from three published research studies was used as an outgroup for an inter-population genetic study. The analysis showed that the mean value of the observed heterozygosity was 0.29 ± 0.14, and the expected heterozygosity was 0.72 ± 0.14, which indicated low genetic diversity. The inbreeding coefficient, F_IS, was high, at 0.46. Significant (p < 0.01) deviations from the Hardy Weinberg equilibrium were noted for all loci. The bottleneck analysis using the Wilcoxon Rank test under the two-phase model of mutation was significant (p < 0.01) for heterozygosity excess, which suggested that the Katjang breed had undergone significant population reduction in the past. Through combined analysis of data from publicly available research, almost the entire population of Katjang goats represent the centroid and are grouped together on a multidimensional scaling plot, except for the Terengganu population. Network analysis revealed that the goat population from Pahang formed the centrality of the network.

中文翻译：

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马来西亚半岛原产加影山羊的微卫星遗传特征

Katjang山羊是马来西亚唯一的本地家养山羊品种。根据2001年至2002年的全国基线调查，该品种已报告给粮农组织，处于灭绝的危险。在这项研究中，筛选了36个微卫星标记，并使用25个多态性标记分析了马来西亚半岛Katjang山羊品种的遗传结构。来自三项已发表研究的另外10个人群的样本数据被用作人群间遗传研究的外群。分析表明，所观察到的杂合度的平均值为0.29±0.14，预期杂合度为0.72±0.14，表明遗传多样性低。近交系数F _IS高，为0.46。显著（p对于所有基因座，均记录了<0.01）与Hardy Weinberg平衡的偏差。在两阶段突变模型下，使用Wilcoxon Rank检验进行的瓶颈分析对于杂合度过高是显着的（p <0.01），这表明Katjang品种过去经历了显着的种群减少。通过对来自公开研究的数据进行综合分析，除登嘉楼（Terengganu）种群外，几乎所有加影山羊（Katjang）山羊都代表了质心，并按多维比例图进行了分组。网络分析表明，彭亨州的山羊种群构成了网络的中心。