Abstract

The present work highlights the broad range of oxygen and nitrogen heterocycles and their applications in medicinal field. A facial approach has been developed for the synthesis of coumarinyl xanthenes and acridine derivatives via one pot multicomponent reaction using green chemical technique. All the isolated compounds were characterized by spectral analysis such as IR NMR and mass. Compounds were screened for their antibacterial and anti-inflammatory activity. While, biological activity results of synthesized coumarin derivatives are quite significant and contribute to the medicinal chemistry.

中文翻译：

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黄原二酮和A啶二酮的无溶剂合成，表征和体外生物活性研究

摘要

本工作着重介绍了氧和氮杂环的广泛范围及其在医学领域中的应用。已经开发出一种面部方法用于通过绿色化学技术通过一锅多组分反应来合成香豆素基黄嘌呤和a啶衍生物。所有分离的化合物均通过光谱分析（例如IR NMR和质量）进行表征。筛选化合物的抗菌和抗炎活性。同时，合成香豆素衍生物的生物活性结果非常重要，并有助于药物化学。