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Bioinspired Gold Nanoparticle Synthesis Using Terminalia bellerica Fruit Parts and Exploring Their Anti‐bacterial Potency In Vitro
Indian Journal of Microbiology ( IF 2.1 ) Pub Date : 2021-04-11 , DOI: 10.1007/s12088-021-00937-3
Akhila Chithambharan 1 , Lalitha Pottail 2 , Rekha Manjunath Mirle 3 , Ravimoorthy Rajalakshmi 1 , Aruna Ponnusamy 1
Affiliation  

Gold nanoparticles with their excellent biocompatibility are extensively used in pharma and biological applications. Terminalia bellerica (TB) dry fruit parts mediated gold nanoparticles were synthesized using the aqueous extracts. The secondary metabolites screening of the aqueous extracts was done using phytochemical analysis. The green synthesized gold nanoparticles show vibrant colours. They were characterized using UV–Visible spectroscopy, FT-IR spectroscopy, XRD analysis and FE-SEM. The analytical characterization methods ensured the formation of nanoparticles and could predict the nanometric size of the nanoparticles. The study also lay to determine the antibacterial potential of the TB fruit parts and TB fruit parts mediated gold nanoparticles. The pathogens chosen for the study were pathogens from clinical species such as Acinetobacter pneumonia, Bacillus subtilis, and Enterococcus faecalis which cause common infections. The TB fruit part extracts, as well as TB fruit parts mediated gold nanoparticles were capable enough to destroy clinical pathogens.



中文翻译:

利用榄仁果实部分进行仿生金纳米粒子合成并探索其体外抗菌效力

金纳米粒子具有优异的生物相容性,广泛用于制药和生物应用。榄仁(TB) 干果部分介导的金纳米粒子是使用水提取物合成的。使用植物化学分析对水提取物进行次级代谢物筛选。绿色合成的金纳米粒子显示出鲜艳的色彩。使用紫外-可见光谱、FT-IR 光谱、XRD 分析和 FE-SEM 对它们进行了表征。分析表征方法确保了纳米颗粒的形成,并可以预测纳米颗粒的纳米尺寸。该研究还旨在确定结核果实部位和结核果实部位介导的金纳米粒子的抗菌潜力。选择用于研究的病原体是来自临床物种的病原体,例如肺炎不动杆菌枯草芽孢杆菌粪肠球菌。导致常见的感染。结核果实部位提取物以及结核果实部位介导的金纳米粒子足以破坏临床病原体。

更新日期:2021-04-11
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