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Bioinspired Gold Nanoparticle Synthesis Using Terminalia bellerica Fruit Parts and Exploring Their Anti‐bacterial Potency In Vitro

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Abstract

Gold nanoparticles with their excellent biocompatibility are extensively used in pharma and biological applications. Terminalia bellerica (TB) dry fruit parts mediated gold nanoparticles were synthesized using the aqueous extracts. The secondary metabolites screening of the aqueous extracts was done using phytochemical analysis. The green synthesized gold nanoparticles show vibrant colours. They were characterized using UV–Visible spectroscopy, FT-IR spectroscopy, XRD analysis and FE-SEM. The analytical characterization methods ensured the formation of nanoparticles and could predict the nanometric size of the nanoparticles. The study also lay to determine the antibacterial potential of the TB fruit parts and TB fruit parts mediated gold nanoparticles. The pathogens chosen for the study were pathogens from clinical species such as Acinetobacter pneumonia, Bacillus subtilis, and Enterococcus faecalis which cause common infections. The TB fruit part extracts, as well as TB fruit parts mediated gold nanoparticles were capable enough to destroy clinical pathogens.

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Acknowledgements

We would like to acknowledge Bharat Ratna Prof.C.N.R Rao Research Centre, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore for providing instrumental and infrastructural facilities. We wholeheartedly express our gratitude towards GURUKADAKSHAM Trust for providing financial assistance in terms of Fellowship. Financial assistance from DST-CURIE for procurement of chemicals is acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India

    Akhila Chithambharan, Ravimoorthy Rajalakshmi & Aruna Ponnusamy

  2. Department of Chemistry and Bharat Ratna Prof.C.N.R Rao Research Centre, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India

    Lalitha Pottail

  3. Department of Chemistry, SoS, B-II, Jain (Deemed to be University), Bangalore, India

    Rekha Manjunath Mirle

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  1. Akhila Chithambharan
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Correspondence to Lalitha Pottail.

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Chithambharan, A., Pottail, L., Mirle, R.M. et al. Bioinspired Gold Nanoparticle Synthesis Using Terminalia bellerica Fruit Parts and Exploring Their Anti‐bacterial Potency In Vitro. Indian J Microbiol 61, 298–305 (2021). https://doi.org/10.1007/s12088-021-00937-3

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