Cacao polyphenols (CPs) are known to suppress the oxidation of low-density lipoprotein and cholesterol absorption. Herein, we examined the impact of CP on the lipid metabolism in rats fed CP-rich chocolate, by analyzing liver weight and histology, via hematoxylin-eosin staining. The high-CP group had significantly lighter livers than the CP-free group. Histologically, the high-CP group showed significantly lower liver fat accumulation than the CP-free group. These results suggest that CPs prevent liver fat accumulation, being potentially useful against obesity and related diseases.

中文翻译：

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可可多酚摄入对大鼠脂质代谢的剂量依赖性作用

已知可可多酚（CPs）可以抑制低密度脂蛋白的氧化和胆固醇的吸收。本文中，我们通过苏木精-曙红染色分析肝脏重量和组织学，检查了CP对饲喂富含CP的巧克力的大鼠脂质代谢的影响。高CP组的肝脏比无CP组的肝脏轻得多。从组织学上讲，高CP组比无CP组显示出明显更低的肝脂肪积聚。这些结果表明，CPs可以防止肝脏脂肪积聚，对肥胖症和相关疾病具有潜在的帮助。