Monitoring the flow rate, cumulative loss and temperature of sweat can provide valuable physiological insights for the diagnosis of thermoregulatory disorders and illnesses related to heat stress. However, obtaining accurate, continuous estimates of these parameters with high temporal resolution remains challenging. Here, we report a platform that can wirelessly measure sweat rate, sweat loss and skin temperature in real time. The approach combines a short, straight fluid passage to capture sweat as it emerges from the skin with a flow sensor that is based on a thermal actuator and precision thermistors, and that is physically isolated from, but thermally coupled to, the sweat. The platform transfers data autonomously using a Bluetooth Low Energy system on a chip. Our approach can also be integrated with advanced microfluidic systems and colorimetric chemical reagents for the measurement of pH and the concentration of chloride, creatinine and glucose in sweat.

监测汗液的流速、累积损失和温度可以为诊断与热应激相关的体温调节障碍和疾病提供有价值的生理学见解。然而，以高时间分辨率获得这些参数的准确、连续估计仍然具有挑战性。在这里，我们报告了一个可以无线实时测量出汗率、出汗量和皮肤温度的平台。该方法结合了一个短而直的流体通道，以捕获从皮肤中流出的汗液，并结合一个基于热致动器和精密热敏电阻的流量传感器，该传感器与汗液物理隔离但热耦合。该平台使用片上蓝牙低功耗系统自主传输数据。