Sand flies (Diptera: Psychodidae: Phlebotominae) are the vectors of Leishmania parasites, which are the causal agents of leishmaniasis. In this work, the survival and developmental time of the immature sand fly stages of Nyssomyia neivai and Migonemyia migonei were studied under laboratory conditions for one generation. Sand flies were collected in a rural dwelling of San Ramón de la Nueva Orán, Salta, Argentina and conditioned in individual rearing containers at 25±2 °C and 80–90% humidity. A total of 38 females of Ny. neivai oviposited 1,392 eggs (\(\overline{\mathrm x}\) = 40.81±16.5) in 5.6 days whereas two females of Mg. migonei oviposited 119 eggs (\(\overline{\mathrm x}\) = 59.50±4.95) in seven days. Migonemyia migonei presented a higher hatching percentage (66.39%) than Ny. neivai (60.99%), without statistical differences between the species (p > 0.05). A total of 78 adults of Ny. neivai emerged (5.60%) while 27 adults (22.69%) emerged for Mg. migonei (p < 0.0001). The survival curves of both species showed that the mortality decreased in the last stages and tended to constant values. This is the first study about the life cycle of sand flies present in northern part of province of Salta, the most endemic area of tegumentary leishmaniasis in Argentina. These results would allow the sustained study of sand flies in the laboratory to deepen the knowledge and understanding of their biology. Finally, it would contribute to elucidate the epidemiological role of the most abundant sand fly species in our study area where Leishmania (Viannia) braziliensis prevails.

白蛉（双翅目：Psychodidae：白蛉）是向量利什曼原虫寄生虫，它们是利什曼病的致病剂。在这项工作中，在实验室条件下研究了奈瑟氏菌和米格米蝇的未成熟沙蝇阶段的存活和发育时间。沙蝇收集在阿根廷萨尔塔省SanRamónde la NuevaOrán的一个农村住宅中，并置于单独的饲养容器中，温度为25±2°C，湿度为80-90％。共有38位Ny女性。neivai 在5.6天内产卵1,392个卵（\（\ overline {\ mathrm x} \） = 40.81±16.5），而两名雌性Mg产卵。migonei产卵119卵（\（\ overline {\ mathrm x} \）  = 59.50±4.95）在七天内。迁移的Migonemyia migonei（66.39％）比Ny高。neivai（60.99％），物种间无统计学差异（p> 0.05）。共有78位Ny成人。neivai出现（5.60％），而27名成年人（22.69％）出现了镁。migonei（p <0.0001）。两种物种的生存曲线都表明死亡率在最后阶段下降，并趋于恒定。这是关于萨尔塔省北部存在的沙蝇生命周期的首次研究，萨尔塔省是阿根廷被皮膜性利什曼病最流行的地区。这些结果将使在实验室中对沙蝇进行持续的研究，以加深对其生物学的认识和了解。最后，这将有助于阐明在巴西利什曼原虫（Viannia）巴西盛行的研究区域中最丰富的沙蝇物种的流行病学作用。