Objectives

Inflammatory bowel disease (IBD) is a chronic and idiopathic gastrointestinal pathology whose bi-directional relation with psychological variables (e.g., quality of life, fatigue, and stress) has been studied in depth. Dispositional mindfulness has been related to a better quality of life and health in chronic diseases. The present study aims to examine the potential mediator influence of dispositional mindfulness in the association between disease severity and health-related quality of life, stress, and fatigue in IBD patients.

Methods

In a cross-sectional study, 152 patients diagnosed with IBD were recruited from the digestive unit of Sagunt Hospital (Spain) where they were receiving treatment. Dispositional mindfulness, fatigue, perceived stress, health-related quality of life, and illness severity were measured. Subsequently, descriptive statistical analyses, Pearson product-moment correlations, multivariate analysis of variance, and mediation analyses were performed.

Results

Dispositional mindfulness facets were positively associated with quality of life, lower fatigue, and lower perceived stress levels (except for the observe subscale). Mediation analyses showed that IBD severity (moderate vs. mild patients) indirectly influenced quality of life (ab = −6.16, 95% CI [−13.46, −0.76]), perceived stress (ab = 2.23, 95% CI [0.41, 4.24]), and fatigue (ab = 3.24, 95% CI [0.48, 6.66]) through its effect on the dispositional mindfulness facet “acting with awareness.”

Conclusions

Dispositional mindful awareness seems to be a protective factor in addition to a promising intervention target in IBD patients, whose severity only influences quality of life, perceived stress, and fatigue through it.

中文翻译：

---

性格正念与炎症性肠病：正念意识介导严重程度与生活质量，压力和疲劳之间的关系

目标

炎性肠病（IBD）是一种慢性和特发性胃肠道病理，其与心理变量（例如生活质量，疲劳和压力）的双向关系已得到深入研究。性格方面的正念与慢性病患者生活质量和健康状况的改善有关。本研究旨在研究IBD患者疾病严重程度与健康相关的生活质量，压力和疲劳之间的关系中性格正念的潜在中介因素影响。

方法

在一项横断面研究中，从Sagunt医院（西班牙）的消化科招募了152名诊断为IBD的患者，他们正在接受治疗。测量了性格上的正念，疲劳，感觉到的压力，与健康相关的生活质量以及疾病的严重程度。随后，进行了描述性统计分析，Pearson乘积矩相关性，方差的多元分析和中介分析。

结果

性格正念方面与生活质量，较低的疲劳度和较低的感知压力水平呈正相关（观察分量表除外）。中介分析显示，IBD严重程度（中度患者与轻度患者）间接影响生活质量（ab = −6.16，95％CI [−13.46，-0.76]），感知压力（ab = 2.23，95％CI [0.41、4.24] ]）和疲劳（ab = 3.24，95％CI [0.48，6.66]）通过其对性格正念方面的影响“以意识行事”。

结论

除了对IBD患者有希望的干预目标外，性格上的正念意识似乎是一种保护性因素，IBD患者的严重程度仅会影响生活质量，感知的压力和疲劳。