In this essay, a tunable metamaterial-based biosensor is proposed for simultaneous monitoring of blood components including cells, plasma, water, thrombus, and urine components as well as glucose, albumin, and urea. The proposed biosensor is based on optical sensors, and it provides real-time, label-free, and direct detection, small size, and cost-effectiveness that can be an alternative tool to other conventional methods. The influence of operating frequency, sample thickness, temperature, and radiation angle on the performance of the sensor is investigated by the finite element method (FEM). Numerical results show that the maximum sensitivity and figure of merit (FoM) in the high frequency are 500 (nm/RIU) and 2000, and for low frequency are 136 (µm/RIU) and 155, respectively. The footprint of the structure is 0.34 µm2, which is remarkably smaller than the other reported biosensing structures. The proposed biosensor has the potential to provide high sensitivity, high FoM, and a wide operating range for biomedical applications.

在本文中，提出了一种可调谐的基于超材料的生物传感器，用于同时监测血液成分，包括细胞，血浆，水，血栓和尿液成分以及葡萄糖，白蛋白和尿素。所提出的生物传感器基于光学传感器，并且提供了实时，无标签，直接检测，体积小和成本效益高的特点，可以作为其他常规方法的替代工具。通过有限元方法（FEM）研究了工作频率，样品厚度，温度和辐射角度对传感器性能的影响。数值结果表明，高频下的最大灵敏度和品质因数（FoM）分别为500（nm / RIU）和2000，而低频下的最大灵敏度和品质因数（FoM）分别为136（µm / RIU）和155。该结构的占地面积为0.34 µm2，比其他报道的生物传感结构要小得多。提出的生物传感器具有为生物医学应用提供高灵敏度，高FoM和宽泛的工作范围的潜力。