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Design and Simulation of a Novel Tunable Terahertz Biosensor Based on Metamaterials for Simultaneous Monitoring of Blood and Urine Components

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Abstract

In this essay, a tunable metamaterial-based biosensor is proposed for simultaneous monitoring of blood components including cells, plasma, water, thrombus, and urine components as well as glucose, albumin, and urea. The proposed biosensor is based on optical sensors, and it provides real-time, label-free, and direct detection, small size, and cost-effectiveness that can be an alternative tool to other conventional methods. The influence of operating frequency, sample thickness, temperature, and radiation angle on the performance of the sensor is investigated by the finite element method (FEM). Numerical results show that the maximum sensitivity and figure of merit (FoM) in the high frequency are 500 (nm/RIU) and 2000, and for low frequency are 136 (µm/RIU) and 155, respectively. The footprint of the structure is 0.34 µm2, which is remarkably smaller than the other reported biosensing structures. The proposed biosensor has the potential to provide high sensitivity, high FoM, and a wide operating range for biomedical applications.

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All data included in this paper are available upon request by contact with the contact corresponding author.

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Authors and Affiliations

  1. School of Electrical and Computer Engineering, Lorestan University, Khoramabad, Iran

    Hamed Emaminejad, Ali Mir & Ali Farmani

Authors
  1. Hamed Emaminejad
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  2. Ali Mir
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  3. Ali Farmani
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Contributions

Hamed Emami Nejad: Software, Data curation, Investigation. Ali Mir: Conceptualization, Methodology, Writing—review and editing. Ali Farmani: Validation, Data curation, Writing—original draft.

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Correspondence to Ali Farmani.

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Emaminejad, H., Mir, A. & Farmani, A. Design and Simulation of a Novel Tunable Terahertz Biosensor Based on Metamaterials for Simultaneous Monitoring of Blood and Urine Components. Plasmonics 16, 1537–1548 (2021). https://doi.org/10.1007/s11468-021-01399-5

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