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Evolutionary Aspects of Genomic Imprinting
Molecular Biology ( IF 1.5 ) Pub Date : 2021-02-26 , DOI: 10.1134/s0026893320060102
E. A. Sazhenova , I. N. Lebedev

Abstract—

Genomic imprinting is an epigenetic phenomenon that differentiates maternal and paternal copies of genes in the genome and causes monoallelic expression depending on parental origin. Imprinting is an evolutionary puzzle, as it bears the costs of diploidization without its advantages, namely, protection from recessive mutations. The aim of this review is to answer the question of why genomic imprinting arose and became fixed in the evolution of angiosperms, insects, marsupials, and placental mammals.



中文翻译:

基因印记的进化方面

摘要-

基因组印记是一种表观遗传现象,可以区分基因组中母本和父本的基因拷贝,并根据亲本的来由引起单等位基因表达。印记是一个进化难题,因为它承担了二倍体化的成本,却没有它的优势,即防止隐性突变。这篇综述的目的是回答为什么在被子植物,昆虫,有袋动物和胎盘哺乳动物的进化中,基因组印记会出现并固定下来的问题。

更新日期:2021-02-26
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