The review highlights the need of non-antibacterial, non-antifungal and non-anticancer characters of metal or metal oxide nanoparticles. The usage of nanoparticles as a part of therapeutic measures results in certain unfavourable effects. The nanoparticles can disturb healthy gut microorganisms that may bring about some health damages regarding pathogenic diseases, obesity, and inflammation likewise. Even the nonspecific interactions of nanoparticles with healthy cells and tissues can cause altered expressions of various pro-inflammatory factors and stress related genes. This review indicates and prospect about the demand of nanoparticles with non-antibacterial, non-antifungal and non-anticancer properties. Such nanoparticles will be effective in various remedial and diagnostic purposes.

该综述强调了金属或金属氧化物纳米粒子对非抗菌、非抗真菌和非抗癌特性的需求。使用纳米粒子作为治疗措施的一部分会导致某些不利影响。纳米颗粒会干扰健康的肠道微生物，同样可能对致病性疾病、肥胖和炎症造成一些健康损害。甚至纳米颗粒与健康细胞和组织的非特异性相互作用也会导致各种促炎因子和压力相关基因的表达发生改变。本综述指出并展望了对具有非抗菌、非抗真菌和非抗癌特性的纳米粒子的需求。这种纳米颗粒将在各种治疗和诊断目的中有效。